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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Sigolene on August 28, 2000, at 7:12:22
I've just read in a psychpharmalogical book that the sedation with Remeron or Desyrel is not dose dependant.
i.e. the sedation should be the same with a very low dosage than with normal dosage.
For the ones with experience on these meds, is that true ?
Posted by Greg on August 28, 2000, at 7:30:01
In reply to Remeron/ Desyrel, posted by Sigolene on August 28, 2000, at 7:12:22
Sigolene,
I don't have any experience wih the Desyrel, but did take the Remeron for quite a long time. After the initial acclamation period my experience with it was the higher dose (45mgs) was less sedating than the lower doses (15-30mgs). My pdoc told me this would happen, and while I thought HE was the one in need of therapy, it turned out he was right. I've heard this has been the case with others too. The Rem eventually stopped working for my depression and continued it because it helped with my sleeping (I'm an insomniac). I discontinued it because the weight gain I experienced with it was more than I could tolerate. I hope this helps.
Greg
> I've just read in a psychpharmalogical book that the sedation with Remeron or Desyrel is not dose dependant.
> i.e. the sedation should be the same with a very low dosage than with normal dosage.
> For the ones with experience on these meds, is that true ?
Posted by JaneST on August 28, 2000, at 18:52:21
In reply to Re: Remeron/ Desyrel » Sigolene, posted by Greg on August 28, 2000, at 7:30:01
S.
I can only reiterate what Greg has told you...I was a zombie 20 minutes after taking 15mgs Remeron...literally would fall in to the bed...but on 30mgs can take it and stay up practically most of the night. No experience on the desyrel...
Hope this helps,
Jane
Posted by allisonm on August 28, 2000, at 19:48:01
In reply to Remeron/ Desyrel, posted by Sigolene on August 28, 2000, at 7:12:22
If you go to the "sedation" folder within the "side effects" folder of the Remeron eGroups site (http://www.egroups.com/links/psycho-babble-tips/Remeron_000963366608/Side_effects_000963366721)
You'll find a wealth of threads and posts on the subject of Remeron, dose and sedation.
Hope this helps.
Allison
Posted by JohnL on August 29, 2000, at 5:26:15
In reply to Remeron/ Desyrel, posted by Sigolene on August 28, 2000, at 7:12:22
> I've just read in a psychpharmalogical book that the sedation with Remeron or Desyrel is not dose dependant.
> i.e. the sedation should be the same with a very low dosage than with normal dosage.
> For the ones with experience on these meds, is that true ?...No. Not in my experience. As with everything else, responses will vary dramatically from one person to the next. I think it's inaccurate for a piece of literature to make such a sweeping blanket statement.
Remeron sometimes is more activating at higher doses, while being very sedating at lower doses. But with some people, like me, it just got more and more sedating at higher doses.
Desyrel is supposed to be good for sleep. Not with me. It caused me very restless nightmarish headachy sleep.
I learned to take what I read with a grain of salt. All that really matters is how a particular med behaves in your body, not how it behaved in someone else's. They aren't the same.
John
Posted by afatchic on August 31, 2000, at 19:53:57
In reply to Re: Remeron/ Desyrel, posted by JohnL on August 29, 2000, at 5:26:15
I took Desyrel (Trazodone) for several years and found that the drowsiness WAS dose dependent. Of course everyone is unique in their responses. I've read several sources that claim that Desyrel (Trazodone) is not an effective AD and is best used as a sleep aid. For me, it was a life saver and I only needed 50mg a night to be effective. The intense drowsiness and morning hang-over should wear off after the first few weeks.
> > I've just read in a psychpharmalogical book that the sedation with Remeron or Desyrel is not dose dependant.
> > i.e. the sedation should be the same with a very low dosage than with normal dosage.
> > For the ones with experience on these meds, is that true ?
>
>
>
> ...No. Not in my experience. As with everything else, responses will vary dramatically from one person to the next. I think it's inaccurate for a piece of literature to make such a sweeping blanket statement.
>
> Remeron sometimes is more activating at higher doses, while being very sedating at lower doses. But with some people, like me, it just got more and more sedating at higher doses.
>
> Desyrel is supposed to be good for sleep. Not with me. It caused me very restless nightmarish headachy sleep.
>
> I learned to take what I read with a grain of salt. All that really matters is how a particular med behaves in your body, not how it behaved in someone else's. They aren't the same.
> John
Posted by caroline on September 3, 2000, at 2:39:15
In reply to Remeron/ Desyrel, posted by Sigolene on August 28, 2000, at 7:12:22
Sigolene
I've no experience with Desyrel, but 30mg of Remeron was a powerful sedative for me, while 45mg has turned it into a stimulant. I've had to augment it with a tricyclic in order to get more than three hours sleep at night! I'm aware that these chemicals effect different people in very different ways, the variable being the brain chemistry we each start out with, but I've read many posts here from people who, like me, have found the effect of a chemical underwent radical change at a higher or lower dose.
I'm aware many people have replied to your mail with similar experiences. I guess I just wanted to add mine in the hope it could help you.
Best wishes
Caroline
Posted by JaneST on September 3, 2000, at 12:10:13
In reply to Re: Remeron/ Desyrel, posted by JohnL on August 29, 2000, at 5:26:15
All:
Anyone with experience with Remeron at 45mgs? I was supposed to up it from 30mg to 45mgs and for two nights became a zombie that couldn't function...which lasted well into the next day. Is this something that just happens when getting used to the new dosage?...I was hoping it would be activating... Any thoughts?
Jane
Posted by allisonm on September 5, 2000, at 20:19:48
In reply to Re: Remeron/ Desyrel, posted by JaneST on September 3, 2000, at 12:10:13
Hi Jane,
Unlike some, I always found more sedation with the higher dose of Remeron. 45mg was the most sedating. I can't remember what it was like when I went from 30 to 45. I do remember having to drink coffee in the morning "to get rid of the cobwebs" when I was at 45. I suspect the zombie feeling will taper off as you get accustomed to it. I know when I first started taking Rem it hit me like a ton of bricks, but that wore off.
Good luck all.
Allison
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