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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by SalArmy4me on August 4, 2001, at 21:55:59
Does it have beneficial effects in unipolar depression without psychotic symptoms?
Posted by Elizabeth on August 5, 2001, at 8:21:58
In reply to Is There Any Evidence 4 Amisulpride In Depression?, posted by SalArmy4me on August 4, 2001, at 21:55:59
> Does it have beneficial effects in unipolar depression without psychotic symptoms?
Low doses of amisulpride have been found to be effective for dysthymia and residual depression (major depression in partial remission), as well as for negative symptoms in schizophrenia. Its pharmacologic effects differ at low vs. high doses.
At a minimum, I'd expect it to be useful at least as an augmentor in major depression. It seems like it would be worth checking out.
-elizabeth
Posted by jotho on August 5, 2001, at 21:30:13
In reply to Re: Is There Any Evidence 4 Amisulpride In Depression?, posted by Elizabeth on August 5, 2001, at 8:21:58
Hello Elizabeth...
It would seem that amisulpride is more difficult now to obtain...not to mention fairly expensive. JohnL has mentioned several other possible substitute anti-P's for low-dosage trials with depression. I would like to hear your comments and suggestions (advantage/disadvantage of one over another) on this if you'd be so kind. Thanks, jotho
Posted by Sigolène on August 6, 2001, at 8:49:53
In reply to Re: Is There Any Evidence 4 Amisulpride In Depression? » Elizabeth, posted by jotho on August 5, 2001, at 21:30:13
I would just like to add that for me amisulpride was useless, i tried it long enough and at the right dose. I have dysthymia and depression.
Sigolène
Posted by Elizabeth on August 6, 2001, at 12:12:53
In reply to Re: Is There Any Evidence 4 Amisulpride In Depression? » Elizabeth, posted by jotho on August 5, 2001, at 21:30:13
> It would seem that amisulpride is more difficult now to obtain...not to mention fairly expensive. JohnL has mentioned several other possible substitute anti-P's for low-dosage trials with depression.
Can you point me to a particular post? I'm not sure which ones you mean.
Amisulpride has a pretty unique profile; I don't think that any of the antipsychotics available in the U.S. would be a real substitute.
-elizabeth
Posted by jotho on August 6, 2001, at 12:48:49
In reply to Re: Is There Any Evidence 4 Amisulpride In Depression? » jotho, posted by Elizabeth on August 6, 2001, at 12:12:53
> > It would seem that amisulpride is more difficult now to obtain...not to mention fairly expensive. JohnL has mentioned several other possible substitute anti-P's for low-dosage trials with depression.
>
> Can you point me to a particular post? I'm not sure which ones you mean.
>
> Amisulpride has a pretty unique profile; I don't think that any of the antipsychotics available in the U.S. would be a real substitute.
>
> -elizabethHi Elizabeth...
Sorry, dumb of me not to include the names.
Yes, JohnL says the same about the uniqueness of amisulpride, but mentions in many posts zyprexa and risperdal (sp?) as a possible alternative. It seems many of the reliable overseas pharmacies are being pressured by the FDA into refusing the sale of amisulpride, though it is not a controlled substance. Anyhoo, do you have any comment on the two AntiP's mentioned?
Thanks again in advance.....john
Posted by Elizabeth on August 7, 2001, at 9:02:01
In reply to Re: Is There Any Evidence 4 Amisulpride In Depression?, posted by jotho on August 6, 2001, at 12:48:49
> It seems many of the reliable overseas pharmacies are being pressured by the FDA into refusing the sale of amisulpride, though it is not a controlled substance. Anyhoo, do you have any comment on the two AntiP's mentioned?
Zyprexa and Risperdal? Yes: neither of them should be considered a substitute for amisulpride (IMO), although they do help some people with depression.
-elizabeth
This is the end of the thread.
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