Shown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Denise528 on January 2, 2002, at 10:20:07
I am really frustrated, I used to take prothiaden and then 5 years later Seroxat, came off the Seroxat 4 years ago, went back on for a brief period in that time. They both worked with great success. I became depressed again in June and have since tried Remeron, Seroxat, Zooloft, Celexa and now prozac, none of which have worked, not even a slight improvement. Can somebody please explain to me why this has happened? Have i Jeopardised my chances of them working by discontinuing them and then starting them again?
Also, has anyone else had this experience?
Any feedback would be really appreciated.
Thx....Denise
Posted by MB on January 3, 2002, at 10:02:54
In reply to Won't work third time around/Any other experiences, posted by Denise528 on January 2, 2002, at 10:20:07
> I am really frustrated, I used to take prothiaden and then 5 years later Seroxat, came off the Seroxat 4 years ago, went back on for a brief period in that time. They both worked with great success. I became depressed again in June and have since tried Remeron, Seroxat, Zooloft, Celexa and now prozac, none of which have worked, not even a slight improvement. Can somebody please explain to me why this has happened? Have i Jeopardised my chances of them working by discontinuing them and then starting them again?
>
> Also, has anyone else had this experience?
>
> Any feedback would be really appreciated.
>
> Thx....Denise
I've been on the medication merry-go-round for over ten years. One thing I've noticed over the years about starting and stopping meds is that Not only have I become less and less tolorant to almost all psychiatric medications, but those medications that used to work almost instantaneously no longer do anything for me but make me sick (e.g., Effexor). Personally, I don't think the brain ever goes back to baseline after being on one of these meds. That's a good thing if you get on the right med because you might, one day, be "cured." However, pdocs have no real way of finding the "right" medication for us. Our mental anguish allows us to justify being their guinnea pigs. My brain is way worse off than it was 10 years ago when I started these meds, but I keep trying them because the pain is so great. I'm playing the lottery and paying with my mind.MB
Posted by CalvaryHill on January 6, 2002, at 1:25:24
In reply to Won't work third time around/Any other experiences, posted by Denise528 on January 2, 2002, at 10:20:07
It seems to me that you are trying mostly serotonergic medicines. Perhaps you can achieve remission with norephrine-dominant medicines like desipramine, nortriptyline, or maprotiline.
Posted by Denise528 on January 9, 2002, at 9:03:14
In reply to Re: Won't work third time around/Any other experiences » Denise528, posted by CalvaryHill on January 6, 2002, at 1:25:24
> Thanks for the advice but I have already tried prothiaden (a tryciclic), doesn't this also effect norepinephrine? Also, Last time I was depressed Seroxat worked beautifully, the depression is and feels the same this time so why doestn't a serotonin acting drug work? I guess I am looking for a Scientic explanation as to why they have stopped working? I was thinking about trying effexor, is this an SSRI and is it the same as Remeron. I've been so dissapointed this time round and I thought it would be so easy. They should put a warning on the literature telling people that if you discontinue the drug they are liable not to work the next time around. If only I had known.
Denise
This is the end of the thread.
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