Psycho-Babble Medication Thread 114888

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Phenobarb question

Posted by geno on August 2, 2002, at 1:09:47

My doc swithed me to pheno barb to wean me off xanax. I feel withdrawls from xanax. I take 60mg a day? Isnt pheno in the same gaba catagory as xanax? I dont feel right on this med.
can someone explain this to me.
geno

 

Re: Phenobarb question

Posted by katekite on August 2, 2002, at 13:26:22

In reply to Phenobarb question, posted by geno on August 2, 2002, at 1:09:47

Hi Geno,

Phenobarb binds to a site on the GABA receptor, and so do the benzodiazepines like Xanax. Both enhance the nice mellow inhibitory effect of our natural GABA.

However, phenobarb and Xanax reach different concentrations in different parts of the brain. Also they may 'like' some types of GABA receptors more than others.

So they have slightly different profiles. This means withdrawal will be helped some by phenobarb but you will definitely still experience some symptoms.

Hang in there,

Kate

 

Re: Phenobarb question

Posted by geno on August 2, 2002, at 17:54:18

In reply to Re: Phenobarb question, posted by katekite on August 2, 2002, at 13:26:22

Well i talked to my doc today. he said to up the pheno barb to 60mg every 2 hrs until hit hits me. He said it takes alot longer than xanax. I can see how xanax is so addictive compared to phenobarb or other long actiing meds. Yes i feel withdrawls, such as tighness in the face, dysphoria, mild panic, insomnia, excitement, raised heart rate. Sorta feels like my brain is convusing a bit. I was taking 1mg of xanax split 2 x a day, then stopped stone cold onto pheno. Do you think i should get back on xanax and taper, such as take .25 2x a day for a week?

geno


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