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Dr. Bob is Robert Hsiung, MD,
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Posted by smokey on December 18, 2002, at 19:50:33
In reply to Monthly Update of my Experience on Effexor, posted by h20surfer1 on December 10, 2002, at 0:13:15
I, too, started on Effexor (the XR). I've been on it a month, am up to 75mg. Started on 37.5 for 2 weeks, then 75. It's for depression/anxiety. Have been on (over the last 11 years) nortryptyline (pooped out), then Celexa, which after a while "hypered me up" too much. Affected my sleep too much. I tried Wellbutrin but felt like a raging bull.
Effexor has been great. I have good energy- drink a cup of coffee in the morning and I can get a lot done! I have a positive outlook, the worry is greatly decreased. My sleep is much better now. Not too many side effects, some dry mouth, no GI effects. I feel a little fuzzy but much better than when I take nothing! Compared to me off the ADs, this is better (though not perfect.)
Overall, it suits me. I was worried after reading others' bad experiences, but I tried it. My appetite has decreased, I don't have the carbo cravings I did on Celexa. But, I sure miss the wonderful dreams I had on Celexa!
As for sex life, well, how to put it delicately? Libido OK, orgasm is 4 or 5 little ones compared to one regular one before. (I'm female.) Guess I can't complain............
> I have been posting monthly.
>
> I take 225mg/day of Effexor and was started on 15mg/day of Remeron 30 days ago (for Libido problems from Effexor). I have been on effexor for almost 6 months now.
>
> I am still having positive results from Effexor. No depression, no loss in energy, very little anxiety (too much of a reduction and you lose motivation) great sleep (Remeron really helped this), and my libido is slowly starting to return.
>
> I am overall very happy with the results of the meds and will continue to take them until I am directed by the Doc to stop. I have to honestly say that I feel better now than I have since childhood.
>
> Hope this helps for some of you coming to this sight just starting out. The side effects go away and the results have been worth it for me.
Posted by johnj on December 18, 2002, at 21:15:16
In reply to Re: Monthly Update of my Experience on Effexor, posted by smokey on December 18, 2002, at 19:50:33
HI Smokey,
I am currently taking notryptline and about a year ago started having problems after starting to excercise. Upping the dose makes things worse and lowering the dose almost did the same. Sleep has been horrible. How long did it take for the nortr to poop out on you? I started taking it at 27 years of age and that was 10 years ago. I can't seem to excercise which is very frustrating. Could you tell me if you tried any other TCA's and HOW did you get off nortryptline?
Thank you very much
johnj
Posted by Kris21 on December 19, 2002, at 3:10:29
In reply to Re: Effexor XR? Successful but very ugly!, posted by blueheron on December 16, 2002, at 20:18:48
I've been on Effexor XR for 6 months now. 75mg a day. I was previously on Prozac for 3 months but didn't sit well with me. The Effexor has definitely helped, especially in the first few months but i can't help feeling that i'm still not all the way there or that the effexor is losing its effectiveness. Not sure if depression is still somewhat there or if it is side effects causing problems. I feel tired and could sleep all day. Have occassional heart palpitations and anxiety that my heart is gonna stop. Not sure if I need to up dosage or if that would make things worse. Thinking about switching to the new lexapro (new form of Celexa), or adding something on top of the effexor like wellbutrin. I've done lots of research in hopes of finding an answer so i can have my life back to the way it was. It just seems like there is little hope for complete recovery. I'm also afraid to stop the effexor. I have tried weening off it and have those terrible withdrawl symptoms like the whooshing sound and electrical shock sensations and severe anxiety. Trying to fight this desease seems more depressing than the depression itself! On another note, I'm positive that my depression and anxiety was a result of ecstacy use. Are there any meds that work best specifically for ecstacy-related depression?
I'm desperately seeking answers...
Posted by daizy on December 19, 2002, at 8:42:19
In reply to My Effexor experience, posted by Kris21 on December 19, 2002, at 3:10:29
> I've been on Effexor XR for 6 months now. 75mg a day. I was previously on Prozac for 3 months but didn't sit well with me. The Effexor has definitely helped, especially in the first few months but i can't help feeling that i'm still not all the way there or that the effexor is losing its effectiveness. Not sure if depression is still somewhat there or if it is side effects causing problems. I feel tired and could sleep all day. Have occassional heart palpitations and anxiety that my heart is gonna stop. Not sure if I need to up dosage or if that would make things worse. Thinking about switching to the new lexapro (new form of Celexa), or adding something on top of the effexor like wellbutrin. I've done lots of research in hopes of finding an answer so i can have my life back to the way it was. It just seems like there is little hope for complete recovery. I'm also afraid to stop the effexor. I have tried weening off it and have those terrible withdrawl symptoms like the whooshing sound and electrical shock sensations and severe anxiety. Trying to fight this desease seems more depressing than the depression itself! On another note, I'm positive that my depression and anxiety was a result of ecstacy use. Are there any meds that work best specifically for ecstacy-related depression?
> I'm desperately seeking answers...Kris, I know what your going through cause its happening to me also. Ive got depression& anxiety, and am also sure a lot of its down to previous drug use. Im just trying to stop effexor, was on 150, am now down to 37.5, and the withdrawal is bad. Im stopping it cause I think it made me worse, the side effects were horrible. Whats weird is that trying to find an AD to make me feel better is actually making me feel worse as Im starting to think it might never happen, and I'll always feel this bad. How long were you using Ecstacy for, are you still doing it? Im not sure if I should just go back to doing it because if im never going to feel normal again, then I might as well try and enjoy myself how and when I can (trouble is that its kind of not the same as it was in the beginning). I havnt yet been put on on any other meds, but feeling better than when I was on the effexor, so i suppose thats one good thing.................. Here's hoping!
Posted by Kris21 on December 19, 2002, at 14:28:38
In reply to Re: My Effexor experience, posted by daizy on December 19, 2002, at 8:42:19
> > I've been on Effexor XR for 6 months now. 75mg a day. I was previously on Prozac for 3 months but didn't sit well with me. The Effexor has definitely helped, especially in the first few months but i can't help feeling that i'm still not all the way there or that the effexor is losing its effectiveness. Not sure if depression is still somewhat there or if it is side effects causing problems. I feel tired and could sleep all day. Have occassional heart palpitations and anxiety that my heart is gonna stop. Not sure if I need to up dosage or if that would make things worse. Thinking about switching to the new lexapro (new form of Celexa), or adding something on top of the effexor like wellbutrin. I've done lots of research in hopes of finding an answer so i can have my life back to the way it was. It just seems like there is little hope for complete recovery. I'm also afraid to stop the effexor. I have tried weening off it and have those terrible withdrawl symptoms like the whooshing sound and electrical shock sensations and severe anxiety. Trying to fight this desease seems more depressing than the depression itself! On another note, I'm positive that my depression and anxiety was a result of ecstacy use. Are there any meds that work best specifically for ecstacy-related depression?
> > I'm desperately seeking answers...
>
> Kris, I know what your going through cause its happening to me also. Ive got depression& anxiety, and am also sure a lot of its down to previous drug use. Im just trying to stop effexor, was on 150, am now down to 37.5, and the withdrawal is bad. Im stopping it cause I think it made me worse, the side effects were horrible. Whats weird is that trying to find an AD to make me feel better is actually making me feel worse as Im starting to think it might never happen, and I'll always feel this bad. How long were you using Ecstacy for, are you still doing it? Im not sure if I should just go back to doing it because if im never going to feel normal again, then I might as well try and enjoy myself how and when I can (trouble is that its kind of not the same as it was in the beginning). I havnt yet been put on on any other meds, but feeling better than when I was on the effexor, so i suppose thats one good thing.................. Here's hoping!I know the feeling of just wanting to say screw it all and pop another pill. BUT DON"T DO IT! Ecstacy seriously fucks your brain up and you will just get worse and worse. I did it for about a year, but only once every couple months. My problem was that i did several in one night when i did it. The key is to stay clean and sober and try to find the right AD for you. I also take 5-htp which is a supplement that helps replace serotonin. exercise, diet, and a positive outlook also help. i know it's hard, but to me i have no other choice. what other meds have you taken? i'm thinking of switching to lexapro, the newest one out.
hang in there...Kris
Posted by smokey on December 19, 2002, at 21:49:15
In reply to Re: Monthly Update of my Experience on Effexor » smokey, posted by johnj on December 18, 2002, at 21:15:16
Hi johnj-
I was on nortryptyline about 7-8 years. Sometimes I could taper it off and be without for up to a year. That's not true now. I didn't have problems with exercise. What kind do you mean? At the dose I mostly needed I needed to sleep 10 hours a night to feel rested. With kids, that was very difficult to get! Then after it started to poop out (got more feelings of depression) my doc suggested an SSRI instead, since a higher dose would not have been tolerable with the amount of sleep I needed. To get off, I just tapered down over about 10 days. I had some stomach cramps and headache, but it was tolerable. Then started the SSRI when at 25mg of nortr. I haven't tried any other TCA's, nortryp was the first medication.
Hope this helps!> HI Smokey,
>
> I am currently taking notryptline and about a year ago started having problems after starting to excercise. Upping the dose makes things worse and lowering the dose almost did the same. Sleep has been horrible. How long did it take for the nortr to poop out on you? I started taking it at 27 years of age and that was 10 years ago. I can't seem to excercise which is very frustrating. Could you tell me if you tried any other TCA's and HOW did you get off nortryptline?
> Thank you very much
> johnj
Posted by daizy on December 20, 2002, at 10:06:01
In reply to Re: My Effexor experience, posted by Kris21 on December 19, 2002, at 14:28:38
>
> I know the feeling of just wanting to say screw it all and pop another pill. BUT DON"T DO IT! Ecstacy seriously fucks your brain up and you will just get worse and worse. I did it for about a year, but only once every couple months. My problem was that i did several in one night when i did it. The key is to stay clean and sober and try to find the right AD for you. I also take 5-htp which is a supplement that helps replace serotonin. exercise, diet, and a positive outlook also help. i know it's hard, but to me i have no other choice. what other meds have you taken? i'm thinking of switching to lexapro, the newest one out.
> hang in there...
>
> Kris
>Yeah I ve decided that im definitely NOT going to take any drugs again, it would just make things worse, and I cant cope with that. I took Amitriptylene (I think thats how You spell it!) For about two months before I started effexor, and that had no efeect at all other than to give me nightmares so I would wake up in the middle of the night and not be able to get back to sleep, So that had to stop. Ive heard about this 5htp, because a friend used to take it before and after doing drugs, not just ecstacy though all sorts!, and she has not had any problems with anxiety or depression. I was just wondering whether its okay to just take it, does it interact with other meds, or do you need doctors advise? For me its the anxiety thats the worst so, im on Valium now, and its good, but soon I wont be able to get any more. I dont know what its like wherever you are but here in England it takes ages for appointments with doctors and to get the right meds. I want to see a phsyc so I can find out the extent of my problems, and they obviously know more about AD's and stuff than doc's do. I dont know, Klonopin sounds like its good for anxiety?.........................
Posted by bingopaja on December 20, 2002, at 11:13:55
In reply to Re: My Effexor experience, posted by daizy on December 20, 2002, at 10:06:01
a year ago i was diagnosed with a brain tumour because i started to have seizures. im on dilantin and clobazam to control them.
now i'm on effexor XR for my depression/anxiety.
i read in the effexor information sheet that you should be carefeful to take it if you have a history of seizure disorders. and then on the web, i've read that effexor is the least likely to cause seizures. and more literature here and there to support both sides.
any one know anything on this legit?
thanks,
phil
Posted by johnj on December 20, 2002, at 17:07:08
In reply to Re: Monthly Update of my Experience on Effexor, posted by smokey on December 19, 2002, at 21:49:15
Thanks for the response
I have not been able to titrate down without serious sleep problems. I could not excercise because I would det dizzy and it would get worse as the days progressed. Also, my sleep would get disturbed. It was like the drug was either increase or decreased. I am thinking of lexapro, but I cannot taper without sleep problems.
Posted by Sioux on December 20, 2002, at 20:38:18
In reply to Re: Monthly Update of my Experience on Effexor » smokey, posted by johnj on December 20, 2002, at 17:07:08
>
> I have not been able to titrate down without serious sleep problems. ... I cannot taper without sleep problems.-----
John, see if Ambien works for you. It's been a charm for me (and I've been on it for a year, believe it or not). It's expensive and insurance balks at paying for it.--S
Posted by jimmygold70 on December 21, 2002, at 12:14:26
In reply to Effexor XR with Wellbutrin?, posted by JESSsMom on December 17, 2002, at 5:18:12
How much Effexor XR are you taking ? Getting the dose up to 225-300mg/day elevates NA levels, which should result in less fatigue and the rest of things.
My 2 cents,
Jimmy
Posted by jimmygold70 on December 21, 2002, at 12:15:56
In reply to Re: Effexor --some little big Qs, posted by Scot_lass2003 on December 17, 2002, at 20:39:01
Mostly it does. Taking the dose up works sometimes. Adding Remeron ("Sun Diego Cocktail") or moving to Remeron should solve this problem.
Jimmy
Posted by mxgirl13 on December 23, 2002, at 9:58:48
In reply to Re: Effexor --some little big Qs, posted by jimmygold70 on December 21, 2002, at 12:15:56
I've been sucessfully taking Effexor XR (3) 75mg capsules per day for 5 years (including therapy and a psychiatrist). Unfortunately, no insurance has forced me to stop taking this in a hurry. I had no problems going to 2 capsules per day. I can do one, but I get dizzy, headache, sweats, and fly off the handle before I know what I'm doing if I wait for more than a day and a half before taking another. Fortunately for this purpose I am unemployed and can handle more symptoms. I have memory problems. I cannot recall words; I get stuck in mid sentence on the smallest thing.
Does anyone have any suggestions for me? How long will I have to muddle through at one pill every day to day and a half while my husband and I suffer (or until they run out)? I tried going 3 days without and it was an utter disaster.
I'm staying away from caffeine and alcohol during this time. Does this help? I am craving carbs like CRAZY.
I am taking .5mg Xanax to get to sleep at night. Is this interfering with the Effexor? I can't get to sleep without it. I feel like I'll just jump right out of the bed if I don't take one to calm down.
I'll appreciate anything anyone has to offer. Thank you so much.
Posted by Geezer on December 23, 2002, at 10:17:03
In reply to Re: Effexor coming off of 5 years use. Help!, posted by mxgirl13 on December 23, 2002, at 9:58:48
> I've been sucessfully taking Effexor XR (3) 75mg capsules per day for 5 years (including therapy and a psychiatrist). Unfortunately, no insurance has forced me to stop taking this in a hurry. I had no problems going to 2 capsules per day. I can do one, but I get dizzy, headache, sweats, and fly off the handle before I know what I'm doing if I wait for more than a day and a half before taking another. Fortunately for this purpose I am unemployed and can handle more symptoms. I have memory problems. I cannot recall words; I get stuck in mid sentence on the smallest thing.
>
> Does anyone have any suggestions for me? How long will I have to muddle through at one pill every day to day and a half while my husband and I suffer (or until they run out)? I tried going 3 days without and it was an utter disaster.
>
> I'm staying away from caffeine and alcohol during this time. Does this help? I am craving carbs like CRAZY.
>
> I am taking .5mg Xanax to get to sleep at night. Is this interfering with the Effexor? I can't get to sleep without it. I feel like I'll just jump right out of the bed if I don't take one to calm down.
>
> I'll appreciate anything anyone has to offer. Thank you so much.You might try substituting a low dose of Prozac for the Effexor every other day for a couple of weeks, then stop the Prozac. This is only my experience but the long half life of Prozac may help the withdrawal. I have never taken Effexor (for the very reasons you mention) but had no withdrawal when I quit Prozac after 18 months. I don't know of any problem with taking the Xanax - seems to me prolonged insomnia would only make matters worse. Hope you have relief soon.
Geezer
Posted by EGR on December 23, 2002, at 15:45:17
In reply to Re: Effexor coming off of 5 years use. Help! » mxgirl13, posted by Geezer on December 23, 2002, at 10:17:03
Why don't you try a 75 and a 37.5 a day for two or three weeks and then drop down to 75? Then alternate between 75 and 112.5 a day for a few weeks and then go down to 75 a day, etc.
Posted by Alara on December 23, 2002, at 23:25:55
In reply to Re: Effexor coming off of 5 years use. Help!, posted by mxgirl13 on December 23, 2002, at 9:58:48
MxGirl,
I came off 75mg a day of EffexorXR cold turkey after four years (owing to an emergency vet bill). The first couple of days were hell, but after 1 week I was feeling almost completely normal. The physical withdrawal process took approximately 7-10 days for me. Try taking a night time cold and flu formula for some relief.
The psychological withdrawal may take longer. I occasionally felt irritable and angry for no reason for about a month after withdrawing. In general, my mood was very good for the first couple of weeks. After that I experienced a few mood swings, which resolved after 2 months or so. (St Johns Wort helped tremendously here.)
Effexor withdrawal is tough, but be assured that you are not dying or going crazy! Hope this helps.
Alara
Posted by askbob on December 24, 2002, at 0:00:59
In reply to Re: Effexor coming off of 5 years use. Help!, posted by mxgirl13 on December 23, 2002, at 9:58:48
My experience with Xanax is it is addictive. I was taking St. John's Wort for anxiety plus Xanax every night at .5mg -- then under stress started increasing it to 1.0mg. At this point it gets addictive, and my nerves were shot. Like a junkie, I started dabbling in various herbal relaxants, and got so screwed up that I ended up in the hospital.
Don't try to save money by doing herbals! Especially stay away from Kava-kava -- it is dangerous when taking a sedative like Xanax.
See if your doctor will switch you to Klonapin -- a safer alternative. I switched, and could not sleep for a week. Eventually it worked, though, and I don't feel so tired every afternoon. I used to feel exhausted every day after work (while taking Xanax before bed).
>
> I am taking .5mg Xanax to get to sleep at night. Is this interfering with the Effexor? I can't get to sleep without it. I feel like I'll just jump right out of the bed if I don't take one to calm down.
>
> I'll appreciate anything anyone has to offer. Thank you so much.
Posted by mxgirl13 on December 24, 2002, at 11:52:07
In reply to Re: Effexor and Xanax -- get off Xanax first, posted by askbob on December 24, 2002, at 0:00:59
Thanks everybody who replied already! I wasn't sure what I'd see back, if anything, but you guys are really great.
I was taking 3-75mg Effexor XR per day, and went down to 2 with no prob. Today is the 2nd day at a day and a half interval between 1-75mg capsules and no dizzyness yet. I guess I can count myself really lucky I don't feel nausia. As I don't have insurance right now, I don't have access to a doctor or new meds. Does anyone know if it's ok to split up the capsule? I was told I couldn't.
I've been able to handle anxiety through behavioral modification and I bet it was almost a year ago since I had to take a Xanax mid day for it. Even then it was just .25mg. I'm stuck on the depression though. I get low and don't feel like doing anything. It's sad because I know when it's happening, but it's not life threatening. That's why with my current circumstances I believe I can do without Effexor.
I've had bouts of insomnia for 10 years now. I was taking Temazepam 15 mg capsules, but I only have 6 left, and I seriously want to keep them for emergencies, so I switched over to .25mg Xanax right at bed time. I have dreams with this, but they are only mildly shocking, so I can deal with them. I go into sleep deprivation on the third day if I don't take anything. If I do manage to fall asleep without meds the dreams are insane. Blood and guts everywhere, beautiful depression dreams, if you've had 'em you'll know I don't appreciate waking up from them.
Thanks, Alara, for your info on going cold turkey. Oh, I'm so afraid of withdraw. It's so awful to experience. I gave up on day 3 of cold turkey because I went crazy on my kid. I mean I hollered a good deal and shoved him in his room, but neither of us appreciated it. Do symptoms for a week start on this day or is it starting from the first day you stopped? I wonder if I was half way there that day. Does the night time cold medicine hang with you the following day? Did you take if every night? Just that week? My doctor said that Tylenol PM sticks with you for 24 hours and makes you slow in the head although you can't really it.
I've never heard of Klonapin (sp?). I'll research it to see if it sounds good for me once I do get insurance again. Thank you for letting me know about it. My psych said the Temazepam was ok to take. Anyone have experience with this? I tried a TON of sleep aids and this is the only one that worked to keep the dreams away and keep me from twiching myself right out of the bed.
Anyone know if memory probs come from Xanax or Effexor? I hear from both. My memory has been worse since Effexor, but I feel especially dingy if I have too much Xanax.
Herbals, yikes! I tried Kava Kava and had a breakdown! It was awful! I did ask my doctor at the time before I tried it, and all he said was that he couldn't say one way or the other about it because it wasn't FDA approved. Thanks, doc.
Merry Christmas everyone!
Posted by dond on December 25, 2002, at 13:32:45
In reply to Re: Anyone had success on Effexor XR? , posted by Glenda on April 14, 2000, at 12:59:09
started effexor xr dec.18th for migraines causing vertigo problems. on 6th day went to Christmas eve midnight service and was about 3 hours late taking medicine. at service was nervous, feel nauseated and had chest palpations. is this normal?
Posted by lynnads on December 25, 2002, at 17:46:39
In reply to Re: Anyone had success on Effexor XR? , posted by dond on December 25, 2002, at 13:32:45
> started effexor xr dec.18th for migraines causing vertigo problems. on 6th day went to Christmas eve midnight service and was about 3 hours late taking medicine. at service was nervous, feel nauseated and had chest palpations. is this normal?
I just started taking Effexor XR not too long ago myself. My doctor warned me about the side effects which include pretty much everything you described (So, in short, it is normal). Lucky for me I haven't had the nausea part, but the heart palpitations are quite prevelant along with a few other really annoying side effects. If you want more information on side effects visit the effexor website http://www.effexor.com
Good luck to you.
Posted by mxgirl13 on December 25, 2002, at 18:12:55
In reply to Re: Effexor and Xanax and Withdraw, posted by mxgirl13 on December 24, 2002, at 11:52:07
Ok, I'm trying cold turkey. This is day 3 1/2. I'm really getting hit hard with the dizzyness, headache, and yes, now nausia. I can't even sit and read. I have to sit in the dark with my eyes shut. Oh, this is hard. Does it get even harder than this as they days go by, or is it just this until I get over this stupid drug???
People who have just started taking this, BEWARE! If you think getting started is hard, you don't want to experience this! I beg you to try any other alternative drug you can first.
Ok, I sound a bit stressed. This is difficult.
Is it alright to take Mylanta and Xanax .25mg at the same time, anyone? What works good against this nausia, except eating?
Posted by Sioux on December 25, 2002, at 18:55:15
In reply to Re: Effexor Withdraw COLD TURKEY, posted by mxgirl13 on December 25, 2002, at 18:12:55
> Ok, I'm trying cold turkey. This is day 3
Oh, my goodness! Cold turkey is not a good idea.
The brain is designed to absolutely resist changes in its very complex chemistry. Drugs that modify the brain chemistry take time to ramp up and time to ramp down, to allow each of the various feedback systems to re-regulate.
The capsules may be opened and the granules divided.
Posted by mxgirl13 on December 25, 2002, at 19:15:50
In reply to Re: Effexor Withdraw COLD TURKEY, posted by Sioux on December 25, 2002, at 18:55:15
Yes, I understand in a perfect world that this is what I should do. I would love to. I'm really glad to hear that I can open the capsules. Is it harmful to me or just really difficult symptom wise to go cold turkey? As lack of insurance is what put me in this situation, I can't get other meds to assist and I only have a few capsules left. What's your recommendation?
> > Ok, I'm trying cold turkey. This is day 3
>
> Oh, my goodness! Cold turkey is not a good idea.
>
> The brain is designed to absolutely resist changes in its very complex chemistry. Drugs that modify the brain chemistry take time to ramp up and time to ramp down, to allow each of the various feedback systems to re-regulate.
>
> The capsules may be opened and the granules divided.
>
Posted by Sioux on December 25, 2002, at 19:24:51
In reply to Re: Effexor Withdraw COLD TURKEY, posted by Sioux on December 25, 2002, at 18:55:15
Source: Meoni P, Hackett D. Poster presentation. Data on file, Wyeth-Ayerst Laboratories.
EFFEXOR® XR (venlafaxine HCl) is indicated for depression, depression with associated anxiety symptoms, and generalized anxiety disorder.
EFFEXOR® XR is contraindicated in patients taking monoamine oxidase inhibitors (MAOIs). EFFEXOR® XR should not be used in combination with an MAOI or within at least 14 days of discontinuing treatment with an MAOI because of potential for serious adverse reactions. Based on the half-life of EFFEXOR® XR, at least 7 days should be allowed after stopping EFFEXOR® XR before starting an MAOI.
The efficacy and safety of EFFEXOR® XR for pediatric use have not been established.
Treatment with venlafaxine is associated with sustained increases in blood pressure (BP) in some patients. Three percent of EFFEXOR® XR patients in depression studies (doses of 75 to 375 mg/day) and 0.4% in generalized anxiety disorder (GAD) studies (doses of 75 to 225 mg/day) had sustained BP elevations. The incidence of sustained increases in BP at doses greater than 300 mg/day has not been fully evaluated. Less than 1% discontinued treatment because of elevated BP. Experience with immediate release venlafaxine in depression studies showed that sustained hypertension was dose related, increasing from 3% to 7% at doses of 100 mg/day to 300 mg/day, to 13% at doses above 300 mg/day. Regular BP monitoring is recommended.
The most common adverse events reported in EFFEXOR® XR placebo-controlled depression trials (incidence >10% and >2x that of placebo) were nausea, dizziness, somnolence, abnormal ejaculation, sweating, dry mouth, and nervousness; and in GAD trials were nausea, dry mouth, insomnia, abnormal ejaculation, anorexia, constipation, nervousness, and sweating.
As with any psychotropic drug, EFFEXOR® XR may impair judgment, thinking, or motor skills; patients should be advised to exercise caution until they have adapted to therapy.
Patients should not be abruptly discontinued from antidepressant medication, including EFFEXOR® XR.
Posted by Sioux on December 25, 2002, at 19:36:32
In reply to Re: Effexor Withdraw COLD TURKEY, posted by mxgirl13 on December 25, 2002, at 19:15:50
>>>> Is it harmful to me or just really difficult symptom wise to go cold turkey? As lack of insurance is what put me in this situation, I can't get other meds to assist and I only have a few capsules left. What's your recommendation?
<<<<<Take the manufacturer's information which I just posted or get it from their website (www.effexor.com \ healthcare professionals) to an emergency room and tell them you need help in doing this and why; also go the hospital's caseworker section and they will identify funding sources for you; the pharmacy may be able to help, too, because manufacturers get tax-breaks for 'mercy' programs; pursue the chaplain's office, if need be, and/or any of the church-supported help lines.
I don't know which of the states you live in; the hoops are different for each one. Be informed, be polite, be persistent. You really should be taking 6 wks - 3 mos to get off the drug.
Take care of yourself! Suffering *is* harmful to you.
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Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
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