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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by ace on January 22, 2003, at 20:43:41
Since being on Nardil, and especially at 90mg, or around abot dose times, I have noticed that sometimes when I smoke (not usually before morning dose) I get a pronounced head spin and dizziness and a little stomach nausea. I have read -- on a very professional monograph -- there is no interaction between Nardil and ciggarettes. Is this true?
BTW, I smoke 8-10 a day.
Posted by Caleb462 on January 22, 2003, at 22:47:09
In reply to NARDIL and tobacco smoking: no interacton?, posted by ace on January 22, 2003, at 20:43:41
There definitely IS an interaction. Nicotine induces dopamine release, nardil inhibits dopamine breakdown - so you're gettting a stronger reaction to the nicotine as far as dopamine concentration than you would normally. There may be other interactions as well.
Posted by cosis on January 22, 2003, at 23:09:57
In reply to NARDIL and tobacco smoking: no interacton?, posted by ace on January 22, 2003, at 20:43:41
Hi Bud
I never notice this problem when I smoke, I smoke about 10 a day too....
Nick
Posted by ace on January 22, 2003, at 23:25:27
In reply to Re: NARDIL and tobacco smoking: no interacton?, posted by Caleb462 on January 22, 2003, at 22:47:09
> There definitely IS an interaction. Nicotine induces dopamine release, nardil inhibits dopamine breakdown - so you're gettting a stronger reaction to the nicotine as far as dopamine concentration than you would normally. There may be other interactions as well.
Yeah, but this doesn't make the blood levels of Nardil to fall. In other words, smoking has no effect on the therapeutic effects of Nardil, albeit your getting a much stronger reaction to the tobacco. Right?
Posted by djmmm on January 23, 2003, at 9:48:09
In reply to Re: NARDIL and tobacco smoking: no interacton? » Caleb462, posted by ace on January 22, 2003, at 23:25:27
It's the tobacco, more so than the nicotine..tobacco inhibits MAO-B...this is well documented, thus the "interacation"
Posted by Caleb462 on January 23, 2003, at 12:11:26
In reply to Re: NARDIL and tobacco smoking: no interacton? » Caleb462, posted by ace on January 22, 2003, at 23:25:27
Correct ace.
This is the end of the thread.
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