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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by Twiggn on March 25, 2003, at 23:34:48
I started taking Wellbutrin SR 100mg qam 10 days ago, in addition to Effexor XR150mg qd and Topamax 100mg bid. I quit Effexor cold turkey 3 days ago. I have a 3+ year history of bulimia, with anoretic features, in remission for about a year and 4 months or so. Since staring the Wellbutrin SR, I have been purging, though not binging excessively although appitite is increasing, several times a day. Purging incidence is increasing. Has anyone ever heard/experienced anything like this before? I'd be really interested in any information anyone has. And yes, my doc knows about my ED history and the seizure risk had been taken into consideration and deemed not an actual risk. Thanks!
Posted by Krissy P on March 26, 2003, at 0:01:23
In reply to Wellbutrin SR and Bulimia Exacerbation, posted by Twiggn on March 25, 2003, at 23:34:48
Hi,
Am I on the right track when I say this?
Could it be that since you say here that your apppetite is increasing, you may feel afraid that you will get fat so your are purging?
I would love to hear back, this post may be replied to more in Psychological Bable though.
I tried Bulimia a few times-I copied someone who was thin. I do not do it now, and I was really getting off on doing it-the few times I did do it.
May sound weird but it's true-it just made me feel like wow, I can eat this fattening stuff and when I purge-my tummy feels flat.
But, it doesn't float my boat personally.
Hang in, Kristen:-)
PS May I also ask about your experience with
Effexor??
Thanks
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> I started taking Wellbutrin SR 100mg qam 10 days ago, in addition to Effexor XR150mg qd and Topamax 100mg bid. I quit Effexor cold turkey 3 days ago. I have a 3+ year history of bulimia, with anoretic features, in remission for about a year and 4 months or so. Since staring the Wellbutrin SR, I have been purging, though not binging excessively although appitite is increasing, several times a day. Purging incidence is increasing. Has anyone ever heard/experienced anything like this before? I'd be really interested in any information anyone has. And yes, my doc knows about my ED history and the seizure risk had been taken into consideration and deemed not an actual risk. Thanks!
Posted by Twiggn on March 26, 2003, at 0:18:22
In reply to Re: Wellbutrin SR and Bulimia Exacerbation » Twiggn, posted by Krissy P on March 26, 2003, at 0:01:23
with the WB, it's more like, in the past few days, every time I eat, I have that familiar compulsion to purge agine and of course I do. But that feeling only starting reappearing since the WB, which is so odd. I don't know if switching fromar, increased norepinephrine to increased dopamine is the culprit or what, but there is definetly something funky going on here.
With effexor, I took it for about a year. After about 6 months I had to double my dose to get it to work again and I quit it the other day cuz it stopped working again, and I have like negative a zillion sex drive and I can't stand it anymore, so no more effexor. SO not worth it, especially since the drug stopped working a while ago. Jus what a depressed person needs--no sex drive and one more reason to be depressed!Thanks!
Posted by zenclear on March 26, 2003, at 0:24:28
In reply to Wellbutrin SR and Bulimia Exacerbation, posted by Twiggn on March 25, 2003, at 23:34:48
> I started taking Wellbutrin SR 100mg qam 10 days ago, in addition to Effexor XR150mg qd and Topamax 100mg bid. I quit Effexor cold turkey 3 days ago. I have a 3+ year history of bulimia, with anoretic features, in remission for about a year and 4 months or so. Since staring the Wellbutrin SR, I have been purging, though not binging excessively although appitite is increasing, several times a day. Purging incidence is increasing. Has anyone ever heard/experienced anything like this before? I'd be really interested in any information anyone has. And yes, my doc knows about my ED history and the seizure risk had been taken into consideration and deemed not an actual risk. Thanks!
Talk to your doc. Bulimia while under the influence of Wellbutrin is associated with seizures. This is clearly stated in the PI etc.
Posted by Krissy P on March 26, 2003, at 0:31:14
In reply to Re: Wellbutrin SR and Bulimia Exacerbation, posted by Twiggn on March 26, 2003, at 0:18:22
Soo true LOL I have a pretty nil sex drive on Effexor too right now, and it doesn't seem to be working for me anymore-I have posted on this so much today but that's ok-that's what we're here for.
At any rate, the Effexor is and has been inducing my mania for the last week or so, and I only just went back on it 3 weeks ago. I am sick of the med. Don't expect to hear me posting good thoughts about it anyore LOLAnyway, thanks and hang in there with the bulimia-I mean obviously be safe k? I'm here for ya!
:-) Kristen
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> with the WB, it's more like, in the past few days, every time I eat, I have that familiar compulsion to purge agine and of course I do. But that feeling only starting reappearing since the WB, which is so odd. I don't know if switching fromar, increased norepinephrine to increased dopamine is the culprit or what, but there is definetly something funky going on here.
> With effexor, I took it for about a year. After about 6 months I had to double my dose to get it to work again and I quit it the other day cuz it stopped working again, and I have like negative a zillion sex drive and I can't stand it anymore, so no more effexor. SO not worth it, especially since the drug stopped working a while ago. Jus what a depressed person needs--no sex drive and one more reason to be depressed!
>
> Thanks!
Posted by Krissy P on March 26, 2003, at 0:36:00
In reply to Re: Wellbutrin SR and Bulimia Exacerbation » Twiggn, posted by zenclear on March 26, 2003, at 0:24:28
Posted by Krissy P on March 26, 2003, at 0:38:04
In reply to Re: Wellbutrin SR and Bulimia Exacerbation » Twiggn, posted by zenclear on March 26, 2003, at 0:24:28
zenclear, so if my pdoc and I decide on Friday to give Wellbutrin a shot, would Lexapro help defeat these possible seizures?? IYHO?
--------------------------------------------------------------------------------------------------Talk to your doc. Bulimia while under the influence of Wellbutrin is associated with seizures. This is clearly stated in the PI etc.
Posted by zenclear on March 26, 2003, at 17:55:19
In reply to Re: Wellbutrin SR and Bulimia Exacerbation » zenclear, posted by Krissy P on March 26, 2003, at 0:38:04
> zenclear, so if my pdoc and I decide on Friday to give Wellbutrin a shot, would Lexapro help defeat these possible seizures?? IYHO?
> --------------------------------------------------------------------------------------------------
>
> Talk to your doc. Bulimia while under the influence of Wellbutrin is associated with seizures. This is clearly stated in the PI etc.
>
>
I don't know. But people with bulimia are advised not to take Wellbutrin, as this combination is associated with increased seizure rate.
Posted by Krissy P on March 26, 2003, at 18:31:19
In reply to Re: Wellbutrin SR and Bulimia Exacerbation » Krissy P, posted by zenclear on March 26, 2003, at 17:55:19
So Wellbutrin when not bulemic=no seizures???Cool! I'm not bulemic and am hoping to give Wellbutrin a shot:-)
Thanks, Kristen
> > Talk to your doc. Bulimia while under the influence of Wellbutrin is associated with seizures. This is clearly stated in the PI etc.
> >
> >
>
>
> I don't know. But people with bulimia are advised not to take Wellbutrin, as this combination is associated with increased seizure rate.
Posted by wendy b. on March 27, 2003, at 8:31:52
In reply to Wellbutrin SR and Bulimia Exacerbation, posted by Twiggn on March 25, 2003, at 23:34:48
Obviously, you know the purging is not healthy. Are you or have you been in therapy about it? You have to get honest with yourself...
My sister has (or had) an eating disorder, anorexia and bulimia for many years, and I think she's over it. But when I talked to her about starting an antidepressant, I warned her about Wellbutrin. I said IF she chose to be up front with her doctor, and talk about the ED, that the doc would probably NOT prescribe the Wellbu. Because of the anecdotal evidence that it could make the ED worse, and if that happened, there is the seizure risk.
So I do not think it's cool at all for your doc to keep you on the Wellbu. Too risky, and pushing you toward unhealthy behaviors that might land you in the hospital, for any number of reasons.
My sis was honest with her doc about the ED, and was prescribed Celexa, and she is doing GREAT on it so far. I asked her how her appetite was, and she said she was finding food interesting again. What a relief...
I hope you can get this figured out - sincerely concerned for your health,
but if you want me to mind my own business, just say so...best wishes,
Wendy
Posted by utopizen on March 27, 2003, at 18:23:14
In reply to Wellbutrin SR and Bulimia Exacerbation, posted by Twiggn on March 25, 2003, at 23:34:48
Posted by Krissy P on March 27, 2003, at 20:23:38
In reply to Try Zofran (nm) » Twiggn, posted by utopizen on March 27, 2003, at 18:23:14
Zofran is for nausea right? I got that in the ER a few times, it works quite well I thought, but I kind of liked compazine (sp) better.
Just a thought...........
Posted by utopizen on March 27, 2003, at 21:36:47
In reply to Zofran........ » utopizen, posted by Krissy P on March 27, 2003, at 20:23:38
> Zofran is for nausea right? I got that in the ER a few times, it works quite well I thought, but I kind of liked compazine (sp) better.
> Just a thought...........It's well-established for also being effective in bulimia and alcohol withdrawl/craving reduction. It targets 5-HT-2 receptors in the brain, which accounts for it's anti-nausea effect. But nausea isn't the only thing that 5-HT-2 affects, so it has these other uses. It is mildly shown to be effective in social anxiety and panic anxiety, although reports are mixed.
Posted by Twiggn on March 28, 2003, at 0:33:04
In reply to Re: Zofran........, posted by utopizen on March 27, 2003, at 21:36:47
Wellbutrin is contraindicated in people with anorexia, bulima (as we all seem to know) kidney disorders and hepatoxicity. This is most likely due to the dehydration factors and the resulting extrodinarily dangerous electrolyte imbalance caused by that dehydration, which in turn will lead to seizures. This is of course, speculatory, because one of the first things in the PI of Wellbutrin, and nearly all AD for that matte, is that the exact mechanism of action is unknown, thus the exact reason for the increased risk of seizure in certain population is also unknown. But an educated guess can be made. So, again thus, if one were to supplement with say water and gatorade the risk of seizure could theoretically be reduced, not that that is any ecxuse for purging. Although the incidence has been reducing, leading me to wonder if it was a side effect of Effexor withdral. Who the heck knows when it comes to screwing around with the brain, ya know?
Thanks for the imput; I appreciate it.
Twiggn
This is the end of the thread.
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