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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by CeeSea on May 4, 2004, at 8:29:25
Anyone know if Edronax and Inderal are contraindicated? I know Edronax can cause tachycardia, so you would almost expect the inderal to help with that. Considering it as an anti-anxiety med, as I can't get klonopin here.
Thanks
CC
Posted by Sad Panda on May 4, 2004, at 13:52:39
In reply to edronax + inderal, posted by CeeSea on May 4, 2004, at 8:29:25
> Anyone know if Edronax and Inderal are contraindicated? I know Edronax can cause tachycardia, so you would almost expect the inderal to help with that. Considering it as an anti-anxiety med, as I can't get klonopin here.
> Thanks
> CCHi CC,
I would expect that would be the case too, but I'm not sure on the interaction between the two with regards to liver enzymes, looks like a perfect question for Chemist. :)
Have you been taking Edronax for long? I am interested to hear about that one. Since you can get Edronax, but can't get Benzos I would guess that you are in the UK?
Cheers,
Panda.
Posted by chemist on May 4, 2004, at 23:39:46
In reply to Re: edronax + inderal = good question for Chemist, posted by Sad Panda on May 4, 2004, at 13:52:39
> > Anyone know if Edronax and Inderal are contraindicated? I know Edronax can cause tachycardia, so you would almost expect the inderal to help with that. Considering it as an anti-anxiety med, as I can't get klonopin here.
> > Thanks
> > CC
>
> Hi CC,
>
> I would expect that would be the case too, but I'm not sure on the interaction between the two with regards to liver enzymes, looks like a perfect question for Chemist. :)
>
> Have you been taking Edronax for long? I am interested to hear about that one. Since you can get Edronax, but can't get Benzos I would guess that you are in the UK?
>
> Cheers,
> Panda.
>
>
>
hi CC and Panda...thanks for the redirect...as a citizen of the US (but not a supporter of any of our government's policies, for those who give a hoot), reboxetine has yet to make it onto our shores....what little i have found indicates that there should be *no* interaction between inderal and reboxetine in re: liver enzymes, as reboxetine is very, very mildly metabolized by CYP4503A4, and inderal is not iplicated in inhibition or induction of this isoenzyme....and as Panda suggests, a benzo might be in your best interst, peut-etre? let us know, and all the best, chemist
Posted by CeeSea on May 5, 2004, at 8:31:07
In reply to Re: edronax + inderal = good question for Chemist » Sad Panda, posted by chemist on May 4, 2004, at 23:39:46
> > Have you been taking Edronax for long? I am interested to hear about that one. Since you can get Edronax, but can't get Benzos I would guess that you are in the UK?
> >
> > Cheers,
> > Panda.Hello Panda,
I am in Australia. I hvae been taking Edronax for the second time since December last year, and I find it helps. I have tried most other modern anti-d's, and a tricyclic, and I either have no reaction or I cannot tolerate the side effects. I tolerate Edronax well, and it has helped to calm the totally irrational states I used to get into. Having said that I am a pretty complex case, so I would never expect any anti-d to work totally for me. So far Edronax is the best.
....and as Panda suggests, a benzo might be in your best interst, peut-etre? let us know, and all the best, chemistThankyou for that Chemist, I am going to discuss it all with my psychiatrist tomorrow. I cannot take benzos as I have a history of severe substance abuse. I think they call it an "addictive personality". It was tried when had maintenance ECT at the start of last year, I was on valium to help with the muscle spasms, and ended up totally hooked. I can only take them occasionally for sleep or a particularly stressful situation. It has been suggested to me by an ex-psych-nurse that beta-blockers may lessen the physical effects of anxiety, which would make the psychological ones easier to deal with. Currently I am on Largactil (anti-psychotic) for its sedative properties, but the side effects of long term use of it bother me greatly, so I am looking at other options.
This forum is great, thanks for the input!
CC
Posted by Sad Panda on May 5, 2004, at 13:17:16
In reply to Re: edronax + inderal = good question for Chemist, posted by CeeSea on May 5, 2004, at 8:31:07
> Hello Panda,
> I am in Australia. I hvae been taking Edronax for the second time since December last year, and I find it helps. I have tried most other modern anti-d's, and a tricyclic, and I either have no reaction or I cannot tolerate the side effects. I tolerate Edronax well, and it has helped to calm the totally irrational states I used to get into. Having said that I am a pretty complex case, so I would never expect any anti-d to work totally for me. So far Edronax is the best.
>
>I am in Australia too. Have you been looked at for possible ADHD?
Cheers,
Panda.
Posted by CeeSea on May 5, 2004, at 20:21:18
In reply to Re: edronax + inderal = good question for Chemist » CeeSea, posted by Sad Panda on May 5, 2004, at 13:17:16
>
> I am in Australia too. Have you been looked at for possible ADHD?
>
> Cheers,
> Panda.
>
No, i guess not, though i have been "diagnosed" with just about everything else. i have double depression (dysthymia plus atypical major dep), some avoidant personality disorder, anxiety, OCD...........those are the ones that make sense anyway. my psych is talking about trying ritalin though, with the 2 anti-d's, 2 anti-psychotics and whatever else he adds by next week. I am a bit over it all at this stage, trying to start a new job and deal with life but not succeeding very well.
thanks for the replies
CC
Posted by chemist on May 5, 2004, at 20:51:19
In reply to Re: edronax + inderal = good question for Chemist, posted by CeeSea on May 5, 2004, at 20:21:18
> >
> > I am in Australia too. Have you been looked at for possible ADHD?
> >
> > Cheers,
> > Panda.
> >
> No, i guess not, though i have been "diagnosed" with just about everything else. i have double depression (dysthymia plus atypical major dep), some avoidant personality disorder, anxiety, OCD...........those are the ones that make sense anyway. my psych is talking about trying ritalin though, with the 2 anti-d's, 2 anti-psychotics and whatever else he adds by next week. I am a bit over it all at this stage, trying to start a new job and deal with life but not succeeding very well.
> thanks for the replies
> CC
>
hi CC.....you'll tough it out, and Panda is clearly more in tune with your meds being a fellow Aussie (although i am an avid AC/DC fan, so i kind of consider myself an honorary Aussie), and Panda knows what he is talking about....keep us informed, will you? with all the best wishes, chemist
Posted by Sad Panda on May 6, 2004, at 16:42:13
In reply to Re: edronax + inderal = good question for Chemist, posted by CeeSea on May 5, 2004, at 8:31:07
Hi CC,
Remeron(Avanza) would be a great alternative to Largactil if you want to use it just for sleep. For me it also help with SSRI type side effects that Effexor gives me.(nausea & anorgasmia) Have you tried Effexor? What side effects did you have with the TCA's?
Cheers,
Panda.
Posted by CeeSea on May 6, 2004, at 19:56:16
In reply to Re: edronax + inderal = good question for Chemist » CeeSea, posted by Sad Panda on May 6, 2004, at 16:42:13
> Hi CC,
>
> Remeron(Avanza) would be a great alternative to Largactil if you want to use it just for sleep. For me it also help with SSRI type side effects that Effexor gives me.(nausea & anorgasmia) Have you tried Effexor? What side effects did you have with the TCA's?
>
> Cheers,
> Panda.
>
Hey Panda
I was on Effexor about 3.5yrs ago, but it made me shake too much (I couldn't do anything cos I shook). Avanza is mirtazapine, right? I took it for about 4 months as an anti-d, but my old doctor took me off it because I was gaining weight and lethargic on it, so I was doing worse things with my diet and stuff. I hadn't heard of it as being used for sleep, though I guess that is a possibility. The TCA was mianserin, which works much the same as amitryptaline, but is gentler re: side effects (Dr Vlad says they give it to old people instead of amitryptaline, cos they tolerate it better). At the time I was working at 8am near the city, and I couldn't wake up enough to drive there. I guess it was too sedating? i tried taking it earlier at night, like 6pm, but found I would fall asleep halfway through cooking dinner if I did that. So it let me sleep but too much, I couldn't function during the day.
Poxy, trying to get a balance between functionality and rest! I like the edronax for it's energy, but insomnia is one of the side effects. I tried seroquel for the first time last night, and it knocked me flat in about 10 minutes (I was talking to my friend in the US and I had to stop cos I was slurring my words, then I passed out in the shower!). The dr gave it to me as anti-anxiety, but I could never take that in the daytime and still function. However it can replace Largactil at night, cos I can sleep and I am not too groggy this morning from it.
So the sleep problem is solved, I just need someting for anxiety symptoms now. Mostly it is the physical ones I need to control (shaking and sweating) 'cos i can talk myself down (in my head) but I can't stop shaking. I played a solo in a concert last week and I had a hard time even standing up cos of the shaking. I know it is normal to be nervous in that situation, but this was way too much, and that was with 25mg largactil in my system.
Dr didn't really want to talk about Inderal, but I am going to keep at him cos it does sound like what I need. He says that cos edronax can lower your blood pressure it would be a bad combo. But I have always had really low blood pressure, and since taking edronax it is actually really high for me (120/80). So I doubt that it would be a problem. I might have to take my mother with me to earbash him on the topic, she thinks it would be good too (she is a nurse, but in ICU).
there isn't really much else to try, I don't want to change the ad, but I can't take benzos. Unless he could give me a chemist controlled supply maybe (one week at a time) so that I couldn't take way too many.
Any other ideas? Sorry, this is waaaaaaay too long!
thanks
CC
Posted by Xanablu on May 9, 2004, at 16:04:38
In reply to Re: edronax + inderal = good question for Chemist, posted by CeeSea on May 6, 2004, at 19:56:16
hi there-
It has taken me about 7 years to find a cocktail that appears to address the majority of my over-all symptoms, both physical (arthritis, chronic back pain, frequent headaches) and nuerobiological.
7 yrs. ago, post-partum at 41 (1st baby), my usually low (110/60) BP rose precipitously. I was in the 'danger zone'. Took the treadmill-echo-cardiagram, & had thorough heart exam.Breezed thru it-outcome: no obvious reason for the chest pain and pressure that had been plaguing me for a few months. I was put on Inderal 120mgs, once daily (extended release). Within a week, bp was back to 110/60 & chest discomfort was controlled.
It was also a good prophylactic headache med. I used to have some sort of HA daily-now-after 7 yrs., they are rare. The cardiologist who dd the heart work-up said he saw no reason for my bp elevation. Told me it was genetic & I shd. plan on taking bp pills forever-just bad luck. However, I have discontinued them at various times, and my bp still remains in the low,
healthy range--even on dexedrine. Go figure.I searched for many years for a good medical support team. Then, high-risk (1st)pregnancy & hormonal shifts, new baby, ill parents and a dx of arth/deg. disc disease, shotgun wedding (at 6 1/2 mos. pg and 40 yrs. old) to boyfriend of a few years and financial problems all contributed to my finally searching doggedly for a med. therp that wd. allow me to function. I had way too much on my plate, & my mental chaos wd. soon become too overt for me to 'just muddle through'.Plus, I had a toddler, a recently widowed mother with Alzheimer's & unresolved private personal 'insanity'
that I HAD to learn to manage, b/c there was no on else to handle thse responsibilities.At 45, I got lucky. Unfortunately, Mother had already passed away, but better late than never. I had fallen into a deep pit of grief and hopeless despair. Then, I was dx'd w/ADD (along w/the previously 'just' classic clinical dep) & prescibed a stimulent.
Hurray! The key to my dilemma. I had been rx'd klonopin for constant muscle tension, by a physiatrist yrs. earlier. That, also was a revelation. My muscles relaxed for the first time in years.After Mom died, I was in constant fibro/arthritic pain. That's when an orthoped suggested I also take Soma, when necessary (only 'muscle relaxer' out of a dz. that ever had any effect). Ihad inquired about this particular drug (carisoprodal) before, because NONE of the 1/2 dz. relaxers I had tried had ever helped at all.(Except the klon.-I use the gemeric, clonazepam made by Teva and find it quite satisfactory).
The Soma was added 6 yrs. after the Inderal and 4 yrs. after the klonopin. The klon. had lost its' property of annihilating physical tension, but had become a lifesaver for what I termed my emotional/intellectual anxiety.
However, I retain the IND. for controlling the very uncomfortable (not to mntion downright scary) 'bodily' symptoms of anxiety. It is the only med I can take, that, within 45", will wipe out all of my physical discomfort-I can breathe deeply and use my stretching & simple yoga routine to 'level out'.When u feel like your heart and lungs are in the grip of King Kong-well, it can truly paralyze u w/fear and pain.
I also have Darvocet on hand for pain, and Vicoprofen for those serious bouts of pain when I've overworked, strained muscles, or simply wake up in a fibromyalgia straight-jacket for who knows what reason. But, I never use these analgesics for the chest pain-for that, they are completely useless.
I take 20 mgs. Lexapro-only AD ever to seem to really help me at all-its presence adds consistency to my anxiety control, helps keep my nightmares and ruminations of doom at bay.
Lots of meds-but i feel better than I have in yrs.
I have good pain control, tolerable anxiety management, more mood stabilization (cd. be better), and, finally, thank god!-the ADD dx and p-stim meds that I have needed for 35 years. Now, I need to begin working hard in the yard again and getting more regular exercise. A great anxiolytic booster.My point-Inderal is wonderful for controlling the physical symptoms of anxiety. It has been a keystone in my recovery process. I now use the imm. release 40mg. pills, and dose myself 2-3 times a day with dose varying somewhat, according to situation. It also has some effect on 'overall' anxiety. It is def'ly worth a try. Exercise caution, however-this med works by signalling the heart to pump more slowly, thereby reducing circulation to some degree. Initial (& perhaps, permanent) side-effects cd. be dizziness and unsteadiness (esp'ly if you rise quickly, before planting both feet firmly on the floor and consciously steadying yourself) and I have def'ly, at times, noticed, a chill in my extremeties. Cold hands & feet can be uncomfortable, but socks at bedtime & gloves when needed are a tolerable trade-off for me.
Hope my life-story did not bore u to tears. Best of luck...& wishin' u
Blue skies, nothin' but blue skies...Xanablu
Posted by CeeSea on May 9, 2004, at 20:55:36
In reply to Re: edronax + inderal = good question for Chemist » CeeSea, posted by Xanablu on May 9, 2004, at 16:04:38
Dear Xanablu
thankyou for that, it helps to know that someone else with low bp can take it and it isn't a prob. I am now on edronax, largactil (but that is going), zyban, xanax and seroquel. the xanax has to go tho, becuase it is addictive (I only ever get 4 tabs at a time from the dr).
I am used to postural drop and cold hands and feet. I don't think those effects would bother me much.
still on at psych about it
CC
This is the end of the thread.
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