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Dr. Bob is Robert Hsiung, MD,
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Posted by ronaldo on November 27, 2006, at 11:17:11
In reply to Adrafanil info please..., posted by Crazy Horse on November 27, 2006, at 11:04:42
> I know nothing about Adrafanil, except i have heard it can increase energy and interest in life, which i am looking for.
>
> 1) What type of med is it i.e., antidepressant, anti-psychotic,etc?
>
> 2) Is it available in the U.S?
>
> 3) Any personal experiences with it?
>
> 4) How does it work? Dopamine? GABA? Etc?
>
> 5) Please, if you have any personal experiences with Adrafanil please tell me how it worked for you..good or bad experiences welcome.
>
> Thank you very much!
>
> -MonteHi Monte
Actually it was blueberry who put me onto Adrafinil (note spelling). Here is a link:
http://www.dr-bob.org/babble/20061123/msgs/706994.html
I have zero experience with it so cannot comment.
You will find all the info you need if you insert Adrafinil in your search engine.
Here is one for starters:
http://www.erowid.org/smarts/adrafinil/adrafinil_info1.shtml
Blueberry has used it for a number of years and will be able to give you all the info.
Also see my thread above:
Avolition anhedonia flat affect cognitive blunting
ciao
....ronaldo
Posted by Crazy Horse on November 27, 2006, at 11:32:31
In reply to Re: Adrafanil info please... » Crazy Horse, posted by ronaldo on November 27, 2006, at 11:17:11
Thanks ronaldo, but i do not believe it's available in the U.S. So then i will go with Wellbutrin. Thanks for your help, at least now i know more about Adrafinil. :)
-Monte
Posted by ronaldo on November 27, 2006, at 11:41:35
In reply to Adrafanil info please..., posted by Crazy Horse on November 27, 2006, at 11:04:42
This is very cheap stuff.
Delivered to your door it works out at about $1 per 300mg tablet. Dose is about 2 to 4 tabs a day. If you take it for more than about 5 months they say you should get your liver enzymes checked. It might be an idea to get your liver checked to start off with so that you get a good baseline.
The liver enzymes are SGOT, SGPT, GGPT and hepatic alkaline phosphatase.
I wish I could help you further with your questions but I am still a Babbler novice and don't understand all the organic chemistry stuff.
ronaldo
Posted by ronaldo on November 27, 2006, at 11:49:23
In reply to Re: Adrafanil info please... » ronaldo, posted by Crazy Horse on November 27, 2006, at 11:32:31
> Thanks ronaldo, but i do not believe it's available in the U.S. So then i will go with Wellbutrin. Thanks for your help, at least now i know more about Adrafinil. :)
>
> -MonteHi Monte,
available from:
[xxx]
I intend to start a course of Adrafinil once I have succeeded in coming off my Olanzapain :-( which will be in a couple of months time.
ronaldo
Posted by Crazy Horse on November 27, 2006, at 12:03:49
In reply to Available in the USA, posted by ronaldo on November 27, 2006, at 11:49:23
> > Thanks ronaldo, but i do not believe it's available in the U.S. So then i will go with Wellbutrin. Thanks for your help, at least now i know more about Adrafinil. :)
> >
> > -Monte
>
> Hi Monte,
>
> available from:
>
> [xxx]
>
> I intend to start a course of Adrafinil once I have succeeded in coming off my Olanzapain :-( which will be in a couple of months time.
>
> ronaldo
>
>
I just ordered a bottle ronaldo, it was $83.00 including shipping. What's the normal dose taken? I got 300 mg. tablets. Thanks.-Monte
Posted by corafree on November 27, 2006, at 12:11:01
In reply to Re: Help...Please. » tensor, posted by Crazy Horse on November 26, 2006, at 18:44:46
Well I'm in the same boat w/ you two ... very flat, bottom fell out ... takes the words right out of my mouth if I had the energy to speak!
posted below, cf
Posted by ronaldo on November 27, 2006, at 12:41:31
In reply to Re: Available in the USA » ronaldo, posted by Crazy Horse on November 27, 2006, at 12:03:49
Hi Monte
I believe the recommended dose is 2 to 4 x 300mg tablets per day. Bear in mind this medication was designed, according to some of the literature, for the elderly who suffer from narcolepsy. I would suggest 2 tablets to start off with taken say 8 am and 2 pm. This is a tablet that keeps you awake so you don't want to take it later than 2 pm but then I don't really know I'm just guessing really. If I remember correctly it has a half life of one hour and takes about 3 weeks to build up.
Blueberry said he/she took it at one tablet per day for a couple of years. Check this out in the avolition anhedonia thread above.
ronaldo
Posted by Crazy Horse on November 27, 2006, at 12:47:24
In reply to Re: Available in the USA, posted by ronaldo on November 27, 2006, at 12:41:31
> Hi Monte
>
> I believe the recommended dose is 2 to 4 x 300mg tablets per day. Bear in mind this medication was designed, according to some of the literature, for the elderly who suffer from narcolepsy. I would suggest 2 tablets to start off with taken say 8 am and 2 pm. This is a tablet that keeps you awake so you don't want to take it later than 2 pm but then I don't really know I'm just guessing really. If I remember correctly it has a half life of one hour and takes about 3 weeks to build up.
>
> Blueberry said he/she took it at one tablet per day for a couple of years. Check this out in the avolition anhedonia thread above.
>
> ronaldoronaldo, you're a great guy..thanks for all your concern and helpful info. I'll babblemail you when i get my adrafinil. :)
-Monte
Posted by ronaldo on November 27, 2006, at 12:54:03
In reply to Re: Available in the USA » ronaldo, posted by Crazy Horse on November 27, 2006, at 12:47:24
Monte,
I will be very interested to see how you get on with the Adrafinil. I will be going on it at the end of January after I have managed to kick this Olanzapain habit I've got. I think you will see the full benefit of it after about 3 weeks - that's what blueberry experienced.
...ronaldo
Posted by Declan on November 27, 2006, at 12:56:54
In reply to Adrafanil info please..., posted by Crazy Horse on November 27, 2006, at 11:00:03
I took Adrafinil for about 6 months, maybe, and still have a heap out the back. Eventually it felt as if it wasn't very nice, and that all the stuff about 'eugregorics' didn't apply to me. It certainly did something though. I ended up with what are described as 'states of inner tension'.
Posted by Crazy Horse on November 27, 2006, at 13:03:51
In reply to Re: Available in the USA, posted by ronaldo on November 27, 2006, at 12:54:03
> Monte,
>
> I will be very interested to see how you get on with the Adrafinil. I will be going on it at the end of January after I have managed to kick this Olanzapain habit I've got. I think you will see the full benefit of it after about 3 weeks - that's what blueberry experienced.
>
> ...ronaldoHey renaldo, have you ever tryed Lyrica? It's a wonderful drug (classified as an anti-epileptic) but has many off label uses including depression and anxiety. I take 300mgs b.i.d., and without it i know i would be bedridden. If you suffer from depression/anxiety look into it. It actually is very activating, but the dose has to be 600 mgs a day. And it takes about 2-3 weeks of tapering to get the full effect. Low dose Lyrica actually is sedating, when you get to 400-600 mgs. it kicks in and is quite stimulating.
-Monte
Posted by Crazy Horse on November 27, 2006, at 13:08:36
In reply to Re: Adrafanil info please..., posted by Declan on November 27, 2006, at 12:56:54
> I took Adrafinil for about 6 months, maybe, and still have a heap out the back. Eventually it felt as if it wasn't very nice, and that all the stuff about 'eugregorics' didn't apply to me. It certainly did something though. I ended up with what are described as 'states of inner tension'.
I'm sorry it didn't work for you Declan. It may not work for me either, but i am sure hoping it will!
-Monte
Posted by ronaldo on November 27, 2006, at 13:10:24
In reply to Re: Available in the USA » ronaldo, posted by Crazy Horse on November 27, 2006, at 13:03:51
> > Monte,
> >
> > I will be very interested to see how you get on with the Adrafinil. I will be going on it at the end of January after I have managed to kick this Olanzapain habit I've got. I think you will see the full benefit of it after about 3 weeks - that's what blueberry experienced.
> >
> > ...ronaldo
>
> Hey renaldo, have you ever tryed Lyrica? It's a wonderful drug (classified as an anti-epileptic) but has many off label uses including depression and anxiety. I take 300mgs b.i.d., and without it i know i would be bedridden. If you suffer from depression/anxiety look into it. It actually is very activating, but the dose has to be 600 mgs a day. And it takes about 2-3 weeks of tapering to get the full effect. Low dose Lyrica actually is sedating, when you get to 400-600 mgs. it kicks in and is quite stimulating.
>
> -MonteThanks Monte, I will keep it in mind. I never realised it was an anti-convulsant.
ronaldo
Posted by ronaldo on November 27, 2006, at 13:23:11
In reply to Adrafanil info please..., posted by Crazy Horse on November 27, 2006, at 11:04:42
> I know nothing about Adrafanil, except i have heard it can increase energy and interest in life, which i am looking for.
>
> 1) What type of med is it i.e., antidepressant, anti-psychotic,etc?
>
> 2) Is it available in the U.S?
>
> 3) Any personal experiences with it?
>
> 4) How does it work? Dopamine? GABA? Etc?
>
> 5) Please, if you have any personal experiences with Adrafanil please tell me how it worked for you..good or bad experiences welcome.
>
> Thank you very much!
>
> -MonteMonte,
Here's some info I have just found:
http://www.remedyfind.com/treatments/0/2625/
Hope it helps
ronaldo
Posted by corafree on November 27, 2006, at 13:30:45
In reply to Re: Available in the USA » ronaldo, posted by Crazy Horse on November 27, 2006, at 13:03:51
Monte I'm only on 75mg Lyrica. When I first took it, the first few days, I felt good, better! Then nothing. Maybe it is responsible for this fatigue. Maybe I should make a call and increase it. You can take it during the day? Wow. I thought it was just to be taken at bedtime. Think I need to make this move?
tks, cf
Posted by KayeBaby on November 27, 2006, at 13:34:07
In reply to Help...Please., posted by Crazy Horse on November 26, 2006, at 18:03:31
> I'm not depressed or anxious, but i have lost my energy (this has been going on for about 3 wks now) i have no motivation, im losing my zest for life, i don't feel like doing much of anything!
>
> I'm thinking i need more dopomine..specifically Wellbutrin. My current drug cocktail is 150 mgs. Zoloft, 300 mgs. Lyrica b.i.d., 1 mg. klonopin b.i.d., and 300mgs. of trazodone at bedtime.
>
> I definitely feel very flat. Any suggestions/ideas will be greatly appreciated. I see my pdoc this week and i was going to ask if i could add on Wellbutrin.
>
> Thanks for listening.
>
> -Monte
>Hey Monte,
I have been on Lyrica for just shy of a year and what I have found is that after a while at the same dose I just go flat. Just blah feeling.Through trial and error I have figured out that Lyrica (at least for me) after a time at the same dosage requires an increase. It acts as though your blood levels are falling and it is as if you are in a constant state of mild withdrawal from the drug.
I have not wanted to increase so I have backed off the dosage when this has happened for just a couple of days or so by taking less more often then I go back up. I do best with this drug taking smaller amounts every 4-5 hrs with bedtime being the largest dose of the day.
Just a thought,
Peace,
Kaye
Posted by corafree on November 27, 2006, at 13:49:09
In reply to Re: Help...Please., posted by KayeBaby on November 27, 2006, at 13:34:07
Kaye .. an interesting and inventive way to handle this.
What is your highest dosage of Lyrica (when you go high w/ it)?
Do you take the highest amount at bedtime (when you go high w/ it)?
tks, cf
Posted by Quintal on November 27, 2006, at 13:49:47
In reply to Re: Adrafanil info please..., posted by Declan on November 27, 2006, at 12:56:54
> I took Adrafinil for about 6 months, maybe, and still have a heap out the back. Eventually it felt as if it wasn't very nice, and that all the stuff about 'eugregorics' didn't apply to me. It certainly did something though. I ended up with what are described as 'states of inner tension'.
I tried adrafinil a while ago along with some other nootropics and felt no effect. I was taking a hefty dose of clonazepam at the time though so perhaps that was masking the stimulant effect?
Q
Posted by corafree on November 27, 2006, at 13:57:13
In reply to Re: Adrafanil info please... » Declan, posted by Quintal on November 27, 2006, at 13:49:47
I'm wondering if my Valium dosage total 25mg a day masked the effect of Provigil too.
cf
Posted by Crazy Horse on November 27, 2006, at 14:07:43
In reply to Re: Available in the USA » Crazy Horse, posted by corafree on November 27, 2006, at 13:30:45
> Monte I'm only on 75mg Lyrica. When I first took it, the first few days, I felt good, better! Then nothing. Maybe it is responsible for this fatigue. Maybe I should make a call and increase it. You can take it during the day? Wow. I thought it was just to be taken at bedtime. Think I need to make this move?
>
> tks, cfYep..call your pdoc and increase the dose to (titrate up of course) 300mgs. a.m. and 300mgs. around 2:00 p.m. You should feel a big improvement. It works very well for my depression. Good luck girl!
-Monte
Posted by Crazy Horse on November 27, 2006, at 14:30:23
In reply to Re: Help...Please., posted by KayeBaby on November 27, 2006, at 13:34:07
> > I'm not depressed or anxious, but i have lost my energy (this has been going on for about 3 wks now) i have no motivation, im losing my zest for life, i don't feel like doing much of anything!
> >
> > I'm thinking i need more dopomine..specifically Wellbutrin. My current drug cocktail is 150 mgs. Zoloft, 300 mgs. Lyrica b.i.d., 1 mg. klonopin b.i.d., and 300mgs. of trazodone at bedtime.
> >
> > I definitely feel very flat. Any suggestions/ideas will be greatly appreciated. I see my pdoc this week and i was going to ask if i could add on Wellbutrin.
> >
> > Thanks for listening.
> >
> > -Monte
> >
>
> Hey Monte,
> I have been on Lyrica for just shy of a year and what I have found is that after a while at the same dose I just go flat. Just blah feeling.
>
> Through trial and error I have figured out that Lyrica (at least for me) after a time at the same dosage requires an increase. It acts as though your blood levels are falling and it is as if you are in a constant state of mild withdrawal from the drug.
>
> I have not wanted to increase so I have backed off the dosage when this has happened for just a couple of days or so by taking less more often then I go back up. I do best with this drug taking smaller amounts every 4-5 hrs with bedtime being the largest dose of the day.
>
> Just a thought,
> Peace,
> KayeThanks Kaye..I think you may be absolutely right. The Lyrica is not as effective as it used to be. Thank you..i will mention it to my pdoc today, however i don't think he'll go higher than 600 mgs.
-Monte
Posted by Crazy Horse on November 27, 2006, at 14:40:27
In reply to Re: Adrafanil info please... » Quintal, posted by corafree on November 27, 2006, at 13:57:13
> I'm wondering if my Valium dosage total 25mg a day masked the effect of Provigil too.
>
> cfcf, my guess is yes. You need the valium, but perhaps(just my opinion) you could slowly lower the dose. My pdoc always preaches to me that benzo's can cause depression..i believe him. I take 1 mg. of Klonopin b.i.d. myself. Lyrica also helps with reducing anxiety, so i can stay at my fairly low benzo dose.
-Monte
Posted by Declan on November 27, 2006, at 14:56:17
In reply to Re: Adrafanil info please... » Declan, posted by Quintal on November 27, 2006, at 13:49:47
I had a nasty experience with Hydergine and Adrafinil. It was a difficult business thing and the combo was quite unhelpful when I really needed something. I had trouble speaking. Not terror, I just felt really strange and inarticulate.
How much Adrafinil did you take, Quintal? I took from 1 to 6 tabs a day, but mostly 2.
Posted by corafree on November 27, 2006, at 15:14:04
In reply to Re: Available in the USA » corafree, posted by Crazy Horse on November 27, 2006, at 14:07:43
None at bedtime Monte? cf
Posted by Quintal on November 27, 2006, at 16:03:20
In reply to Adrafanil and Hydergine » Quintal, posted by Declan on November 27, 2006, at 14:56:17
I can't remember how much I took exactly. Probably much more than recommended knowing me. I was taking it in combo with piracetam and vinpocetine.
>I had trouble speaking. Not terror, I just felt really strange and inarticulate.
I had this problem with olanzapine and lamotrigine. It seemed to take me a few seconds to understand what was being said to me and think of the words to respond properly. Also had difficulty reading.
Q
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