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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by iforgotmypassword on January 25, 2007, at 7:41:04
i was wondering if this is possible.
focused rTMS does not need a seizure.
DBS does not need a seizure.
what if therapeutic effect were wholly dependant on electrical stimulation.
what if higher doses of ketamine than experimented cancelled out the seizure. (preventing glutamate contact at NMDA receptors.)
i think the theory that ect thought damage is caused by glutamate excitoxicity (the seizure is brought on by a glutamte flood reaction) is extremely possible. it could very well not be the electricity "frying" the brain, glial cells or what have you... it may be quite plausible that the electricity could be therapeutic without the seizure? why do other therapies exist without it.
why is it possible for non-seizure inducing magnets to have the therapeutic potential uniform to its MST seizure inducing equivalent practically.
maybe "many times the seizure threshold" is just analagous to the amount of electricity needed for therapeutic effect.
Posted by Phillipa on January 25, 2007, at 11:23:02
In reply to therapeutic ect without the seizure, posted by iforgotmypassword on January 25, 2007, at 7:41:04
I thought the seizure was the benefit? I really don't know but would like to. Love Phillipa
Posted by lcat10 on January 27, 2007, at 12:28:56
In reply to therapeutic ect without the seizure, posted by iforgotmypassword on January 25, 2007, at 7:41:04
Don't know why it is, but apparently the research has shown no benefit from ECT without a tonic-clonic seizure, and the stimulation has to be above the seizure threshold level to a greater or lesser amount.
lcat10
This is the end of the thread.
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