Shown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Klavot on August 8, 2007, at 8:08:05
Fluoxetine and norfluoxetine have very long half-lives. What would be the least often that I could take a 20 mg tablet or capsule of Prozac and still maintain stable blood levels? Are tablets or capsules better?
Klavot
Posted by Quintal on August 8, 2007, at 8:26:41
In reply to Prozac dosing schedule, posted by Klavot on August 8, 2007, at 8:08:05
There's a 90mg preparation of Prozac called 'Prozac Weekly', so that would be it.
Q
Posted by Quintal on August 8, 2007, at 9:13:56
In reply to Prozac dosing schedule, posted by Klavot on August 8, 2007, at 8:08:05
Sorry Klavot, if you only had 20mg tablets and wanted to take it as little as possible I suppose you could take a single 80mg or 100mg dose once a week, or maybe 40mg twice a week. There are formulas for working out the pharmacokinetics of these things but they involve hard sums and therefore out of my league. I would imagine Lar would be able to provide you with more info on that, and the norfluoxetine topic.
Q
Posted by Larry Hoover on August 8, 2007, at 9:29:15
In reply to Prozac dosing schedule, posted by Klavot on August 8, 2007, at 8:08:05
> Fluoxetine and norfluoxetine have very long half-lives. What would be the least often that I could take a 20 mg tablet or capsule of Prozac and still maintain stable blood levels? Are tablets or capsules better?
>
> KlavotThere are two concerns, and you're only looking at one. You can achieve a fairly stable blood level by taking a drug on an interval similar to its half-life. By inference, your blood level will vary by roughly a factor of two. Prozac has a half-life of roughly a week, so that's round about the maximum interval you might consider between doses.
The other factor is total dose. If you take but one 20 mg capsule per week, your daily dose averages only ~3 mg. I would think that dose insufficient to have a very powerful clinical effect.
Lar
Posted by Larry Hoover on August 8, 2007, at 9:34:19
In reply to Re: Prozac dosing schedule » Klavot, posted by Quintal on August 8, 2007, at 9:13:56
> I would imagine Lar would be able to provide you with more info on that, and the norfluoxetine topic.
>
> QI was composing answers to both, as you posted this. Mind-reader?
L
Posted by Phillipa on August 8, 2007, at 11:25:17
In reply to Re: Prozac dosing schedule » Quintal, posted by Larry Hoover on August 8, 2007, at 9:34:19
When the 20mg capsule of prozac came out my pdoc begged me to take one every three days. Reason first day felt really good, second day anxiety, third day panic all day. And this was when I was working and doing well. Love Phillipa
Posted by rjlockhart on August 8, 2007, at 13:25:05
In reply to Re: Prozac dosing schedule » Larry Hoover, posted by Phillipa on August 8, 2007, at 11:25:17
I comsume Prozac 40mg daily. It has helped wit depression, but i think what im hearing is how long does it last?
Prozac lasts up to 3 days i have heard in the body.
Posted by Quintal on August 8, 2007, at 15:24:57
In reply to Re: Prozac dosing schedule » Quintal, posted by Larry Hoover on August 8, 2007, at 9:34:19
Darn it, you've blown my cover Hoover! Yeah, I had one of my 'visions' immediately after pressing the 'Confirm' button for my first post. Nothing to worry about though (I won't tell anyone you post in the nude, or about that banana-shaped birthmark on your...).
Q
Posted by Phillipa on August 8, 2007, at 22:07:12
In reply to Re: Prozac dosing schedule » Larry Hoover, posted by Quintal on August 8, 2007, at 15:24:57
Quintal jelous of bannanas? Lots of good potassium I eat one each morning with breakfast. Love Phillipa
Posted by Klavot on August 9, 2007, at 4:22:21
In reply to Re: Prozac dosing schedule » Quintal, posted by Phillipa on August 8, 2007, at 22:07:12
This is the end of the thread.
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