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Dr. Bob is Robert Hsiung, MD,
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Posted by iforgotmypassword on December 5, 2007, at 6:10:32
i mean:
What is the least sedating, least amnestic/mind-muddling/cognitive-slowing, most Ativan(lorazepam)benzo-like GABA-A agonist or anti-convulsant?
i take Ativan(lorazepam) because it centres my mind and helps me focus to *DO* stuff, and helps a bit with my tardive akathisia. it is not sedating (or minimally) compared to other benzos. problem is it can be amnestic. i forget very easily while using it, and recall of what i did while using it can sometimes be sketchy. i don't think it is great for learning or retaining.
a GABA-A agonist or anticonvulsant, my doctor may be more comfortable with rx-ing one for potential chronic use than a benzo. i figured one of these drugs may be like lorazepam in its benefits, and maybe better and more reliable in its benefits, perhaps more focused in its action, so as to also avoid its amnestic and muddling downsides.
any input would be great. thanks!
Posted by sonic_gb on December 5, 2007, at 7:59:29
In reply to least sedating, most benzolike gaba-a or anticonv, posted by iforgotmypassword on December 5, 2007, at 6:10:32
> i mean:
>
> What is the least sedating, least amnestic/mind-muddling/cognitive-slowing, most Ativan(lorazepam)benzo-like GABA-A agonist or anti-convulsant?
>
> i take Ativan(lorazepam) because it centres my mind and helps me focus to *DO* stuff, and helps a bit with my tardive akathisia. it is not sedating (or minimally) compared to other benzos. problem is it can be amnestic. i forget very easily while using it, and recall of what i did while using it can sometimes be sketchy. i don't think it is great for learning or retaining.
>
> a GABA-A agonist or anticonvulsant, my doctor may be more comfortable with rx-ing one for potential chronic use than a benzo. i figured one of these drugs may be like lorazepam in its benefits, and maybe better and more reliable in its benefits, perhaps more focused in its action, so as to also avoid its amnestic and muddling downsides.
>
> any input would be great. thanks!No Studies to back this up, just personal experience. I find Lorazepam (Ativan) to be quite sedating. For me, clonazepam (Klonopin) and alprazolam (Xanax) are much less sedating, and much more pure anxyolitics. Benzo's aside, I found pregabalin (Lyrica) and gapapentin (Neurontin) helpful for anxiety, and fairly benzodiazepine-like without so many of the drawbacks. IMHO, both of these are JUST as addictive as any benzo, despite literature to the contrary. I have never tried any other AED except for Topiramate (Topamax) which left me so confused that I got lost driving to work, a route that I had been driving daily for over three years... Was that at all helpful? I hope there's something in this post of value.
Sonic
Posted by Justherself54 on December 5, 2007, at 9:11:38
In reply to Re: least sedating, most benzolike gaba-a or anticonv » iforgotmypassword, posted by sonic_gb on December 5, 2007, at 7:59:29
Ativan too sedating for me..clonazapam much better..helps with anxiety..I tried topamax and was constantly doing the "word search" thing..that was a drug trial that didn't last long!
Posted by sonic_gb on December 5, 2007, at 9:54:21
In reply to least sedating, most benzolike gaba-a or anticonv, posted by iforgotmypassword on December 5, 2007, at 6:10:32
There are also thinks like tiagabine or vigabatrin to consider, but those are some pretty heavy duty drugs when it comes to the GABA system.
Posted by Phillipa on December 5, 2007, at 12:18:37
In reply to Re: least sedating, most benzolike gaba-a or anticonv » iforgotmypassword, posted by sonic_gb on December 5, 2007, at 9:54:21
I take valium but am waking up in four hours and then more and in the morning which is stetching til noon even though no bed till 2am. I'm finding myself horribly depressed now didn't happen before in the morning til dark. Any ideas why and would the others taken in past help this? Phillipa
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