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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Phillipa on September 7, 2012, at 12:16:55
There on the web for all to read but subscribe. Intesting as gee who didn't know? Phillipa
Posted by gadchik on September 8, 2012, at 7:16:15
In reply to Ad's Take Time To Work (if they do), posted by Phillipa on September 7, 2012, at 12:16:55
This is a great article,p. I do think doctors dont take enough time to tell patients that they need to give the ads time and that most of the side effects will go away in time. I did stop zoloft, but I took it for 2 yrs.,and it did what it was supposed to do. I just gained too much weight. I probably would be stricter with my eating if I were to ever take it again,and also, it couldve been the remeron that caused weight gain,that's more likely.
Posted by bleauberry on September 8, 2012, at 15:45:19
In reply to Ad's Take Time To Work (if they do), posted by Phillipa on September 7, 2012, at 12:16:55
The statement is generally true.
But it is not universally true. Antidepressants can work as early as Day 1, or within the first week. I've seen it happen to others and experienced it myself. Savella works by day 3 for me, with benefit already evident on day 1. Of the natural substances, rhodiola frequently works beginning day 1 and becoming quite evident by week 1.
Since it is all a pure guess as to which substance to prescribe a patient, and we don't really know what is wrong with their chemistry, whether a med works fast, slow, or not at all I think is determined by how closely that med targets the actual deficiency of that particular patient. If it's off target....for example an SSRI for someone who really needs more help in NE or dopamine, results are probably going to be less than desired.
Many depressions are not caused by a neurotransmitter imbalance or deficiency. No wonder the drugs fail for those people. Too bad they keep looking for the next drug instead of figuring out they are dealing with some other beast not the one they assumed.
More often than not though, the statement is true. They really don't work as claimed very often, and they do generally take a while to cause all the downstream changes to happen.
Posted by Phillipa on September 8, 2012, at 20:14:49
In reply to Re: Ad's Take Time To Work (if they do), posted by gadchik on September 8, 2012, at 7:16:15
I do think this is a factor thinking back. Also some have horrific side effects and decide to discontinue them. P
Posted by Lou Pilder on September 9, 2012, at 17:03:18
In reply to Ad's Take Time To Work (if they do), posted by Phillipa on September 7, 2012, at 12:16:55
> There on the web for all to read but subscribe. Intesting as gee who didn't know? Phillipa
>
>
> http://www.webmd.com/depression/features/antidepressants-take-time-to-work-time-to-quit?ecd=wnl_dep_090712&ctr=wnl-dep-090712_ld-stryFriends,
YOu may be led to believe that there is such a thing as a chemical imbalance in your brain. Does that mean trhat people could be low in benzene so they have to take a drug that has in it's constituancy the chemical benzene? Or do you belive that puttng a metabolite of benzene into your nervous system that will correct such chemical imbalance?
Are you aware that the FDA has sent a warning letter to a drug manufacturer that used the chemical imbalnce phrase, for it is not allowed?
Here is a video from a psychiatrist that talks about "the chemical imbalance theory of psychiatry."
Lou.
To see this video:
A. Pull up Google
B. Type in:
[youtube, what's wrong with psychiatry, a psychiatrist explains].
You will se a pic of a man with a beard.
Posted by SLS on September 9, 2012, at 22:43:33
In reply to Lou's response-the chemical imbalance{redacted} » Phillipa, posted by Lou Pilder on September 9, 2012, at 17:03:18
> Are you aware that the FDA has sent a warning letter to a drug manufacturer that used the chemical imbalnce phrase, for it is not allowed?
No, I wasn't. Where can I find this letter?
Thanks.
At some point, the term "chemical imbalance" must be evaluated semantically. We are made entirely of chemicals, 60% of which is water (the brain is 70% water). I suppose that the physiological anomalies seen in many mental illnesses can be described as imbalances in the chemistry of life. They are just not necessarily imbalances in the amounts of available neurotransmitters.
- Scott
Posted by Novelagent on September 13, 2012, at 15:16:22
In reply to Ad's Take Time To Work (if they do), posted by Phillipa on September 7, 2012, at 12:16:55
ADs take at least 3 months. I saw a doc who would switch me just after 3 weeks to another AD if no changes were seen. Luckily another doc saw me and simply upped my lexapro to 30mg 2 months in. I combined it with selegiline without telling him, 5mg/day along with DLPA.
It's possible the Lexapro made for a sort of lowering of the waters hitting the dam in my brain, along with supportive friends I lived with to role model my behavior around, and the structure I had in going to classes and getting my work done, all helped...
But I also know from day one of taking selegiline and DLPA, just as the hypothesis suggested on this board asserted, I had instant effects. I didn't notice it until 2 weeks into the selegiline, but I hadn't craved sleeping since day 1 of taking it up to then, which was huge for me.
It could have been the synergy of lexapro, but I don't advise combining selegiline with another antidepressant, that can cause a hypertensive crisis or serotonin syndrome.
But I think it is wise to consider emsam (it wasn't available as emsam when I took it) and combine it with DLPA. According to a hypothesis advanced on this board around 2004, DLPA traditionally increases dopamine, but it doesn't build up to anything of a therapeutic benefit because it's constantly being destroyed every few minutes.
Yet selegiline, supposedly, captures the dopamine released by DLPA, allowing it to build up over time, thus explaining why it would yield remission of depression from day one.
I remember smiling in two of my classes on day one of selegiline without noticing it until each of my professors called me out for smiling, curious and assuming it was related to the topic being discussed. Smiling spontaneously was huge for me; my professors likely caught me frowning earlier in the semester, I imagine,or at least not smiling.
> There on the web for all to read but subscribe. Intesting as gee who didn't know? Phillipa
>
>
> http://www.webmd.com/depression/features/antidepressants-take-time-to-work-time-to-quit?ecd=wnl_dep_090712&ctr=wnl-dep-090712_ld-stry
This is the end of the thread.
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