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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by lazylizard on December 9, 2013, at 18:31:13
Anyone here get TD from an antidepressent? I have seen some old posts of a few people but don't know how to reach them. I am looking to see what they did to try and help with it.
Posted by Phillipa on December 9, 2013, at 20:59:49
In reply to Tardive Dyskensia/antidepressents, posted by lazylizard on December 9, 2013, at 18:31:13
No who were the posters? Phillipa
Posted by lazylizard on December 9, 2013, at 21:05:57
In reply to Re: Tardive Dyskensia/antidepressents » lazylizard, posted by Phillipa on December 9, 2013, at 20:59:49
RUKynd
Posted by Phillipa on December 9, 2013, at 22:17:46
In reply to Re: Tardive Dyskensia/antidepressents, posted by lazylizard on December 9, 2013, at 21:05:57
Don't recall that posting name sorry Phillipa
Posted by bleauberry on December 12, 2013, at 15:28:18
In reply to Tardive Dyskensia/antidepressents, posted by lazylizard on December 9, 2013, at 18:31:13
I think we as humans generally tend to downplay the dangers of meds we take. We are, after all, messing with something we know very little about....the brain...and we are doing it with manufactured chemicals that we also know very little about.
That is a potentially scary situation but we do it every day. If TD is the only problem that came out of it, that's not bad.
Does suck though.
I don't know of any effective treatments except for:
1. Time (months minimum, years likely)
2. Calming herbs maybe.
3. Super critical attention to what goes in the grocery cart. Any slight toxin load, pesticides, hormones, man made chemicals, etc, that come to us in foods are enough to prevent healing, and enough to worsen any existing damage.
Posted by sk85 on December 30, 2013, at 12:41:49
In reply to Tardive Dyskensia/antidepressents, posted by lazylizard on December 9, 2013, at 18:31:13
> Anyone here get TD from an antidepressent? I have seen some old posts of a few people but don't know how to reach them. I am looking to see what they did to try and help with it.
I got tardive dystonia from SSRI-s (fluoxetine), about 6-7 years ago. It has actually started to resolve now. It could be spontaneous, but I also think I benefitted from the following things:
- high dose phosphatidylserine
- taking a low dose low potency non-neuroleptic D2 antagonist (e.g. clomipramine, trimetazidine) for a limited period of time (can also cause TD, but you probably know that)
- stress reduction
- botox injectionsThe D2 antagonist benefitted me the most I think, but was pretty complex to use: I first observed this as an unintended effect of clomipramine (prescribed for OCD) and then later from the heart medication trimetazidine (which has D2 blocking effects). Both drugs first slightly increased dystonia, followed by gradual drop off symptoms.
This may or may not apply to tardive dyskinesia.
-Ikaros
Posted by lazylizard on December 30, 2013, at 12:55:56
In reply to Re: Tardive Dyskensia/antidepressents, posted by sk85 on December 30, 2013, at 12:41:49
> > Anyone here get TD from an antidepressent? I have seen some old posts of a few people but don't know how to reach them. I am looking to see what they did to try and help with it.
>
> I got tardive dystonia from SSRI-s (fluoxetine), about 6-7 years ago. It has actually started to resolve now. It could be spontaneous, but I also think I benefitted from the following things:
>
> - high dose phosphatidylserine
> - taking a low dose low potency non-neuroleptic D2 antagonist (e.g. clomipramine, trimetazidine) for a limited period of time (can also cause TD, but you probably know that)
> - stress reduction
> - botox injections
>
> The D2 antagonist benefitted me the most I think, but was pretty complex to use: I first observed this as an unintended effect of clomipramine (prescribed for OCD) and then later from the heart medication trimetazidine (which has D2 blocking effects). Both drugs first slightly increased dystonia, followed by gradual drop off symptoms.
>
> This may or may not apply to tardive dyskinesia.
>
> -IkarosCan you babblemail me? I want to know how long you took the ssri and got the dystonia and also about the treatments you took.
Posted by phidippus on December 30, 2013, at 14:46:51
In reply to Tardive Dyskensia/antidepressents, posted by lazylizard on December 9, 2013, at 18:31:13
Currently, the only approved drug for treating tardive dyskinesia and other movement disorders is tetrabenazine, which is a dopamine depleting drug. The related VMAT2 inhibitor, reserpine, has also been tried in one small randomised double-blind placebo-controlled trial as a treatment for TD with success, as has α-methyldopa. Ondansetron (Zofran) has shown some benefit in experimental studies on tardive dyskinesia and a variety of anti-Parkinsonian medications are used such as donepezil, baclofen, and pramipexole. Clonidine may also be useful in the treatment of TD, although dose-limiting hypotension and sedation may hinder its usage.Botox injections are used for minor focal dystonia, but not in more advanced tardive dyskinesia.Benzodiazepines are an effective treatment for TD, however their use is limited by the development of tolerance which requires ever increasing doses of the benzodiazepines to be used to attenuate TD symptoms. The most popular benzodiazepine for the treatment of TD is clonazepam. Vitamin B6 has been reported to be an effective treatment for TD in two randomised double-blind placebo-controlled trials. In males, the branched-chain amino acid formula Tarvil, containing the amino acids valine, isoleucine, and leucine in a 3:3:4 ratio was reported as beneficial for motor symptoms in a small, non-blinded study.
Eric
This is the end of the thread.
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