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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Sheilac on August 2, 2017, at 18:54:59
I've dropped my dose of Seroquel to 50mg. My muscle pain is gone and my body feels better. I hate to drop it, because I love the sleep I get with it. I'm hoping that I can slowly up it to 100mg. I'm wondering if I go slowly if I can dose back up to 100mg or even higher?
Does anyone know if rapid dosing was the cause of the muscle tightness & pain? Would taking Benedryl prevent the muscle tightness?
Posted by SLS on August 6, 2017, at 5:54:01
In reply to Benedryl + Seroquel?, posted by Sheilac on August 2, 2017, at 18:54:59
> I've dropped my dose of Seroquel to 50mg. My muscle pain is gone and my body feels better. I hate to drop it, because I love the sleep I get with it. I'm hoping that I can slowly up it to 100mg. I'm wondering if I go slowly if I can dose back up to 100mg or even higher?
What's wrong with your sleep?
You are avoiding the Z drugs?
How is your sleep with 50 mg/day of Seroquel? The muscle pain is probably EPS. Perhaps there is another explanation that someone can offer. Either way, I personally would avoid a drug that produced that side effect at dosages that are necessary to gain a therapeutic effect.
You've tried trazodone already?
Maybe hydroxyzine?
Promethazine?
Cyproheptadine?
I would be reluctant to try full dosages of Remeron given your propensity for mania. However, 7.5-15.0 mg might work safely. Most people rave about its sleep-promoting effects.
> > Does anyone know if rapid dosing was the cause of the muscle tightness & pain?
I guess it's possible, but I wouldn't bet on it.
> Would taking Benedryl prevent the muscle tightness?
That's a good thought. I don't like the idea of masking EPS, though. It might hide the development of tardive dyskinesia. I don't know this for sure, but I think it is worth researching. I think you would be better off looking for another drug for sleep before deciding to commit yourself to Seroquel at higher dosages.
If I were in your position, I would try the slow titration of Seroquel as you suggested. You are already taking it. If this becomes problematic, I would look to try low-dosage Remeron or perhaps hydroxyzine.
Linkadge would be the right person to ask about low-dosage amitriptyline and the risk of mania. 25 mg might be okay.
- Scott
Posted by linkadge on August 23, 2017, at 17:16:49
In reply to Re: Benedryl + Seroquel? » Sheilac, posted by SLS on August 6, 2017, at 5:54:01
Magnesium can be good for muscle tightness and may help insomnia / anxiety.
Linkadge
Posted by phidippus on October 7, 2017, at 15:40:43
In reply to Benedryl + Seroquel?, posted by Sheilac on August 2, 2017, at 18:54:59
I'd double check whether the Seroquel was causing the muscle pain. Bring the dosage back up and see if the problem persists. If it does, I would switch antipsychotics. Which ones have you been on?
Eric
Posted by SLS on October 8, 2017, at 12:44:08
In reply to Re: Benedryl + Seroquel?, posted by phidippus on October 7, 2017, at 15:40:43
> I'd double check whether the Seroquel was causing the muscle pain. Bring the dosage back up and see if the problem persists.
That's an excellent idea.
- Scott
This is the end of the thread.
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