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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by PeterMartin on February 20, 2020, at 3:12:47
New study found increased mortality among people with the highest levels of b12.
For some reason b12 pills/shots always make me depressed anyway.
https://www.nytimes.com/2020/02/11/well/live/excess-vitamin-b12-may-be-deadly.html
https://www.insider.com/b12-supplements-could-be-lethal-in-high-doses-study-finds-2020-2?amp
vitamin b12
Having high levels of B12 might not be as good as it sounds. Getty
A study found that people with higher levels of vitamin B12 in their blood plasma had a death rate about twice as high as those with lower B12 levels.
The study looked at 5,571 men and women from the Netherlands over eight years.
This adds to the growing body of research warning people that vitamin supplements may not have as many benefits as they claim.
Visit Insider's homepage for more stories.High levels of vitamin B12 in a person's blood are associated with an increased risk of early death, according to research published last month in the journal JAMA Network Open.
Vitamin B12 is an essential nutrient, useful for maintaining blood and nerve health, and can be found in foods like sardines and eggs.
However, researchers at the University of Groningen in the Netherlands analyzed 5,571 Dutch men and women with an average age of about 54 over about eight years and found that the people with the highest levels of B12 in their blood plasma were more likely to die earlier than those with the lowest levels their death rate was about twice as high.
The team was surprised to find the B12 connection held true even after controlling for other factors like age and history of cancer and heart disease.
The researchers said they weren't sure why, and while it may have something to do with the way B12 affects gut bacteria, they said that's just a guess.
Posted by Hugh on February 20, 2020, at 10:04:06
In reply to Go easy on the b12 supplementing (study), posted by PeterMartin on February 20, 2020, at 3:12:47
I also used to get B12 shots. They made me feel wired. When they wore off, I felt exhausted, and more depressed than usual.
Pregnant women should be very careful with B12 and folate. Women who have very high levels of B12 at the time of giving birth are three times more likely to have a child with autism.
https://www.livescience.com/54711-autism-risk-linked-to-high-folate-levels.html
Posted by linkadge on February 21, 2020, at 7:10:08
In reply to Re: Go easy on the b12 supplementing (study), posted by Hugh on February 20, 2020, at 10:04:06
That's a difficult proposition since it is still generally recommended to supplement with folic acid during pregnancy.
I wonder if there is a correlation between increase prenatal folic acid supplementation over the years and increasing incidence of autism.
Linkadge
Posted by Lamdage22 on February 21, 2020, at 8:51:00
In reply to Go easy on the b12 supplementing (study), posted by PeterMartin on February 20, 2020, at 3:12:47
I came across this recently, too. But I think that high B12 without a B12 Supplement points toward an underlying problem. The underlying problem is the culprit, not the high B12. I'm not sure though.
Posted by Lamdage22 on February 21, 2020, at 8:52:38
In reply to Re: Go easy on the b12 supplementing (study), posted by Lamdage22 on February 21, 2020, at 8:51:00
Posted by undopaminergic on February 21, 2020, at 12:56:42
In reply to Re: Go easy on the b12 supplementing (study), posted by Lamdage22 on February 21, 2020, at 8:51:00
> I came across this recently, too. But I think that high B12 without a B12 Supplement points toward an underlying problem. The underlying problem is the culprit, not the high B12. I'm not sure though.
>I agree. I don't think B12 is at all toxic, except of course that in sufficient amounts, everything is toxic.
-undopaminergic
Posted by Hugh on February 23, 2020, at 12:19:10
In reply to Re: Go easy on the b12 supplementing (study) » Hugh, posted by linkadge on February 21, 2020, at 7:10:08
I've wondered that myself. It's important that pregnant women take folic acid during pregnancy, as it helps to prevent neural tube defects, such as spina bifida. But Dr. Tod Cooperman says that pregnant women should take no more than 400 mcg of folic acid per day, and most prenatal vitamins contain 800 mcg.
> That's a difficult proposition since it is still generally recommended to supplement with folic acid during pregnancy.
>
> I wonder if there is a correlation between increase prenatal folic acid supplementation over the years and increasing incidence of autism.
>
> Linkadge
>
>
Posted by Hugh on February 23, 2020, at 12:23:12
In reply to Re: Go easy on the b12 supplementing (study) » linkadge, posted by Hugh on February 23, 2020, at 12:19:10
Researchers [at Johns Hopkins University] found that if a new mother has a very high level of folate right after giving birth -- more than four times what is considered adequate -- the risk that her child will develop a condition on the autism spectrum doubles. Very high vitamin B12 levels in new moms are also potentially harmful, tripling the risk that her offspring will develop an autism spectrum disorder. If both levels are extremely high, the risk that a child develops the condition increases 17.6 times.
Complete article:
https://hub.jhu.edu/2016/05/12/too-much-folate-pregnant-autism/
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