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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by NoMotic on November 23, 2003, at 15:20:45
I've done a lot of research on Relora in the past few weeks, and it appears to effect a lot of the receptors and hormones I am most interested in: lowers cortisol, raises DHEA, effects serotonin reuptake. To me this is exactly what I need, since one of my key symptoms is extreme sensitivity to caffeine (to me indicating strong cortisol / glucocorticoid feedback failure). I need something to lower stress hormone levels, I've theorized. Yet, when I bought Relora, I found myself actually too sedated for my enjoyment and a bit moody (in a tired way) and decided to stop only after several days. I plan on restarting it again to give it the full test, but what's everyone else's opinion on this? So far, from what I've read from other people taking it, the advertisements make it seem 200% better than it is. What do you think?
Posted by Larry Hoover on November 23, 2003, at 15:50:54
In reply to What's the new consensus on Relora?, posted by NoMotic on November 23, 2003, at 15:20:45
> I've done a lot of research on Relora in the past few weeks, and it appears to effect a lot of the receptors and hormones I am most interested in: lowers cortisol, raises DHEA, effects serotonin reuptake. To me this is exactly what I need, since one of my key symptoms is extreme sensitivity to caffeine (to me indicating strong cortisol / glucocorticoid feedback failure). I need something to lower stress hormone levels, I've theorized. Yet, when I bought Relora, I found myself actually too sedated for my enjoyment and a bit moody (in a tired way) and decided to stop only after several days. I plan on restarting it again to give it the full test, but what's everyone else's opinion on this? So far, from what I've read from other people taking it, the advertisements make it seem 200% better than it is. What do you think?
I'm pretty sure Relora is a Western version of the traditional Chinese remedy Banxia-houpu, but I might be wrong about that. Relora was found to cause 24% incidence of daytime sedation in human trials.
Try a lower dose, and work up, would be my advice.
Lar
Posted by NoMotic on November 23, 2003, at 16:49:46
In reply to Re: What's the new consensus on Relora? » NoMotic, posted by Larry Hoover on November 23, 2003, at 15:50:54
Yeah, I think that's correct. A standarized mix of Phellodendron and Magnolia. I do remember the fact that it could cause sedation, but I was hoping it would cause more of a kava like effect - kava has an extremely strong positive effect on every aspect of my well being, especially motivation and enjoyment of non-immediately rewarding tasks. I wish I knew the exact pharmacological properties of Kava to know what caused this - I know it's most definitely not related to Benzo/Gaba sites, and I suspect it might be related to Norepinephrine reuptake inhibition in the PFC. Or maybe 5-HT1a agonism. What I do know is that Kava is the perfect medication for me, and I usually take it in 7-10 day spurts that make me feel so incredibly good! This is not remotely the same feeling I get from Valerian or St. John's, but it's more similar to a green-tea buzz that's much calmer. It's much more all-encompassing than Valerian or St. John's for me. Of course, I stop after 7-10 days because of the liver toxicity issue, and try to substitute something else in place of it for a month or so, then go back on it. That's why I was trying Relora - hoping to find something similar to Kava. Something that makes me calm, happy, focused, motivated and allows for a large range of actions to be pleasantly rewarding. It's so surprising when I go back on Kava and realise it accomplishes all of these actions so dramatically.
This is the end of the thread.
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