Psycho-Babble Alternative Thread 431002

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Is 5-HTP or Picamilon OK for bipolars?

Posted by catmint on December 17, 2004, at 18:40:53

My depression is chronic and Lamictal is not enough.

Thanks

 

Re: Is 5-HTP or Picamilon OK for bipolars? » catmint

Posted by Larry Hoover on December 18, 2004, at 9:52:37

In reply to Is 5-HTP or Picamilon OK for bipolars?, posted by catmint on December 17, 2004, at 18:40:53

> My depression is chronic and Lamictal is not enough.
>
> Thanks

5-HTP might trigger mania, but individual susceptibility varies dramatically. Using the maxim "Start low, and go slow" vis a vis dose and increases thereof, should keep you out of trouble.

I haven't heard of a picamilon problem with respect to promotion of mania.

Lar

 

Re: Is 5-HTP or Picamilon OK for bipolars? » Larry Hoover

Posted by catmint on December 19, 2004, at 22:15:38

In reply to Re: Is 5-HTP or Picamilon OK for bipolars? » catmint, posted by Larry Hoover on December 18, 2004, at 9:52:37


Thanks.
Can you please compare and contrast the two if you have time?


 

Re: **CAUTION WITH 5-HTP**

Posted by Chairman_MAO on January 11, 2005, at 16:41:32

In reply to Re: Is 5-HTP or Picamilon OK for bipolars? » catmint, posted by Larry Hoover on December 18, 2004, at 9:52:37

5-HTP is, IMHO, at best unreliable and at worst useless and harmful as a medication without a peripheral dopa decarboxylase inhibitor (such as carbidopa). If peripheral dopa decarboxylase is not inhibited, most of the 5-HTP is converted to serotonin before it even reaches the brain, causing a potentially toxic amount of serotonin to enter into systemic circulation. Used long enough and/or at high enough dosages, this very well might cause heart valve problems due to vasoconstriction (remember why fenfluramine was taken off the market ... ?)

 

re: 5htp safety and efficacy........please read

Posted by joebob on January 16, 2005, at 23:44:57

In reply to Re: **CAUTION WITH 5-HTP**, posted by Chairman_MAO on January 11, 2005, at 16:41:32

http://www.mwilliamson.com/5htps.htm

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