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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by RedSoxFan79 on February 2, 2006, at 0:07:48
Anyone have anymore info about the omega-3 DPA. I never even heard about it till tonight?
Posted by nolvas on February 2, 2006, at 20:40:16
In reply to A third Omega-3- DPA (Docosapentaenoic acid) ?, posted by RedSoxFan79 on February 2, 2006, at 0:07:48
Have a look at this (sections 12 and 13)
http://www.omega3sealoil.com/Chapter6_1.html
Posted by RedSoxFan79 on February 2, 2006, at 22:03:09
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by nolvas on February 2, 2006, at 20:40:16
Hmm, I have never heard of seal oil. Is that even legal in the US. I think I would have a hard time swallowing seal oil capsules. I never thought abouth ethics when I was trying fish oil, but I dont think I could do Seal oil. I dont eat Veal or lamb either so I guess it kind of relates.I was doing more researc and discovered yet another Omega-3, Stearidonic acid (18:4) also known as SDA. There was a study done to see if there was a more effective plant based Fatty acid source at increasing omega-3 levels in humans than Flak oil. The study showed that Black Currant Oil, the best source of stearidonic acid, was 4 times more effective at increasing EPA levels in humans than flaxseed oil. Hemp seed oil is also a good source of SDA.
> Have a look at this (sections 12 and 13)
>
> http://www.omega3sealoil.com/Chapter6_1.html
>
>
Posted by nolvas on February 3, 2006, at 5:57:26
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by RedSoxFan79 on February 2, 2006, at 22:03:09
I'm vegetarian so yeah I wouldn't eat seal oil. I also don't eat fish oil the only Omega 3 I can eat is ALA. I've seen vegetarian DHA but it's expensive.
I'm probably not getting all the Omega 3's my body needs being vegetarian, even with some conversion from ALA.It's interesting that you mention Blackcurrant Seed Oil is 4 times more effective at raising EPA than Flaxseed Oil. Could you provide a link? I would be interested thanks. I'm wondering how it works it must be conversion from ALA to EPA? If so why is it 4 times more effective?
Posted by nolvas on February 3, 2006, at 6:01:30
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by nolvas on February 3, 2006, at 5:57:26
My mistake I wasn't reading it carefully enough. It's the SDA that gets converted to EPA. I've seen Blackcurrant Oil in the local Health Shop I will go look later, won't cost much either I suspect.
Posted by nolvas on February 3, 2006, at 6:21:53
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by nolvas on February 3, 2006, at 6:01:30
Sorry to triple post but I just wanted to add this table and a link to a site which has some plant based oils which have a much larger content of SDA.
Conversions of ALA
ALA --d6d-- SDA --e-- ESA --d5d-- EPA --CDA --d4d-- DHA (GOOD)
ALA --d6d-- SDA --e-- ESA --d5d-- EPA --ADA --d4d-- PG3 (GOOD)ALA (18:3w3) Alpha-linolenic Acid. (highest in flax oil)
SDA (18:4w3) Stearidonic Acid. (black currant seeds)
ESA (20:4w3) Eicosa-tetraeonic Acid
EPA (20:5w3) Eicosapentaeonic Acid (oil of cold water fish)
CDA (22:5w3) Clupanodonoc Acid
DHA (22:6w3) Docosahexaeonic Acid (oil of cold water fish)
Posted by PsychoPharmaFiender on February 3, 2006, at 15:21:14
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by nolvas on February 3, 2006, at 6:21:53
I looked at that link you provided, the 2-4 percent of SDA for Black Currant is way Low. Most websites say 9 percent. Ive never heard of the other oils on the table. Here is the link to the study on SDA.
Posted by RedSoxFan79 on February 3, 2006, at 15:28:26
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by PsychoPharmaFiender on February 3, 2006, at 15:21:14
Actually, this is the link to the study that I was talking about. It is much more detailed and informative than the one on pubmed. I wonder where you could get those other oils with the high SDA. Black Current is unique because it also has GLA.
> I looked at that link you provided, the 2-4 percent of SDA for Black Currant is way Low. Most websites say 9 percent. Ive never heard of the other oils on the table. Here is the link to the study on SDA.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12716664&dopt=Abstract
Posted by RedSoxFan79 on February 3, 2006, at 15:29:20
In reply to Re: A third Omega-3- DPA (Docosapentaenoic acid), posted by RedSoxFan79 on February 3, 2006, at 15:28:26
Posted by RedSoxFan79 on February 3, 2006, at 15:31:49
In reply to Here is the link, posted by RedSoxFan79 on February 3, 2006, at 15:29:20
Posted by Larry Hoover on February 5, 2006, at 10:37:29
In reply to A third Omega-3- DPA (Docosapentaenoic acid) ?, posted by RedSoxFan79 on February 2, 2006, at 0:07:48
> Anyone have anymore info about the omega-3 DPA. I never even heard about it till tonight?
You've got to be really vigilant if you're researching DPA, because the same name can be applied to both an omega-6 fatty acid, and an omega-3 fatty acid.
The omega-6 arises from the elongation of arichidonic acid, followed by the delta4 desaturase. The omega-3 arises from the elongation of EPA. They are differentiated by the position of the unsaturated bonds. The full names of these two DPAs are not the same.
In just skimming over some abstracts on Pubmed, I found a number of articles dealing with the adverse effects of omega-6 DPA, and others with respect to the benign effect of the omega-3 structure.
Humans tend to have similar concentrations of EPA and omega-3 DPA in the blood. I have no idea why the biochemistry of the latter fatty acid has been so largely ignored up until now.
Seals, being mammals, apparently have similarly high levels of 3-DPA (that's what I'm going to call it) in their serum and storage lipids. Maybe it makes more sense to use seal oil as a dietary augment than fish oil.
Lar
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