Psycho-Babble Alternative Thread 791031

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Vitex tolerance question.

Posted by cumulative on October 23, 2007, at 23:25:36

Why does it develop so rapidly? The "dopaminergic" effect is quite nice, if not for that I cannot seem to replicate any effect whatsoever for more than two days. Unusual for a dopamine agonist, no?

Dosing ideas, or ideas on attentuating tolerance to this potentially useful agent?

 

Re: Vitex tolerance question.

Posted by toduar on October 24, 2007, at 15:19:30

In reply to Vitex tolerance question., posted by cumulative on October 23, 2007, at 23:25:36

a purely theoretical possibility on my part:
I have read that inositol resensitizes D2 receptors.
although i'm not sure if that is the mechanism involved, since there are d2 agonist meds that don't poop out that fast.

 

Re: Vitex tolerance question.

Posted by valero on October 26, 2007, at 12:00:05

In reply to Vitex tolerance question., posted by cumulative on October 23, 2007, at 23:25:36

When you mean tolerance, I guess that means needing to up the dosage, rather than it simply not working anymore at any dosage. I really like this herb, so far ( 2 weeks continual use) tolerance like that of opiate tolerance hasn't developed, if or when it does I'd try upping the dose, followed by breaks of not using it. Then try stacking it with other herbs.
( was fine with Rhodiola) Bear in mind that Vitex effects will vary from one day to the next, and throughout the day, by very nature of it's endocrine
actions.

 

Re: Vitex tolerance question. )) valero

Posted by cumulative on October 26, 2007, at 15:23:39

In reply to Re: Vitex tolerance question., posted by valero on October 26, 2007, at 12:00:05

I mean that after those two or three days, I can't get it to work for the effect I want (focus) at any dosage whatsoever, but maybe I'm just not trying the right dosages. Do you mind revealing your dosing patterns and some subjective reactions?

It's obvious to me there's a very strong bell curve with this herb, in relation to sought-after effects, where even a slightly modified dosage can give you completely different results, by virtue of the many differing actions it possesses.

 

Re: Vitex tolerance question. )) valero

Posted by valero on October 27, 2007, at 15:01:11

In reply to Re: Vitex tolerance question. )) valero, posted by cumulative on October 26, 2007, at 15:23:39

I take one capsule in the morning, ( Brand Femicur, 4mg concentrated extract of Vitex agnus-castus) and occasionally another in the evening.

Of all the mood boosters I've ever taken, this undoubtedly takes pride of place. The subjective effects have to be "worked for" rather than simply experienced as a drug effect. This is difficult to describe. For me it's more on the level of experienced emotions, rather like a barrior being removed and allowing me to experience the "human condition" in a more understanding way, that there somehow may be a sense to this chaotic and painful existence that we all find ourselves in.

On the physical level, there's a definite increase in strength and appetite for work. A decrease in desire for alcohol consumption. Libido remains intact but tempered. I can't say it does much for my low level of ADHD.

V.

 

Cool, thank you. )) valero

Posted by cumulative on November 1, 2007, at 20:19:22

In reply to Re: Vitex tolerance question. )) valero, posted by valero on October 27, 2007, at 15:01:11

Actually, that sounds a lot like opioid activity, which vitex apparently possesses. Anyone read De Quincey? :)


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