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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by oceancat on October 20, 2008, at 23:52:46
Hi all,
I am looking specifically for a natural dopamine reuptake inhibitor (approximating Wellbutrin's mode of action). I know there's several dopaminergic supplements available, but I can't afford to buy and try them all...any of them reuptake inhibitors that you know of? Wellbutrin was a wonder drug for me but pooped out after a month, and now I'd like to try a natural supplement with magnesium (to prevent tolerance) to see if that'll help.
I'm currently trying Vitex, and while it seems to give me a lot of energy, it's a little buzzy and not particularly mood-lifting so far.
Thanks!
oceancat
Posted by Sigismund on October 21, 2008, at 18:25:17
In reply to Natural dopamine reuptake inhibitor out there?, posted by oceancat on October 20, 2008, at 23:52:46
Yeah, I dunno about DARIs, but I wondered what you thought of Rhodiola.
I liked it but it made my sleep worse.
Posted by oceancat on October 23, 2008, at 1:40:01
In reply to Re: Natural dopamine reuptake inhibitor out there? » oceancat, posted by Sigismund on October 21, 2008, at 18:25:17
Hi,
I am currently trying Rhodiola actually! New Chapter brand from GNC. Rhodiola, from what I've read, is supposed to be stimulating, but I find it calming, with a slight sense of well being. But I'm on a lot of meds and supplements, so... I'm going to continue to take it, maybe try a higher dose over the weekend.
oceancat
Posted by Sigismund on October 23, 2008, at 14:39:41
In reply to Re: Rhodiola » Sigismund, posted by oceancat on October 23, 2008, at 1:40:01
I had a great reaction to deprenyl citrate with rhodiola, but sleep was the limiting factor.
Posted by bleauberry on October 27, 2008, at 18:50:08
In reply to Natural dopamine reuptake inhibitor out there?, posted by oceancat on October 20, 2008, at 23:52:46
St Johns Wort, most especially high hyperforin brands, is a dopamine reuptake inhibitor. Well, in addition to being a reuptake inhibitor of serotonin, norepinephrine, gaba, and glutamate, all with equal affinity.
Posted by ChrisUK88 on January 5, 2009, at 9:33:58
In reply to Natural dopamine reuptake inhibitor out there?, posted by oceancat on October 20, 2008, at 23:52:46
Hi oceancat, you could take 50mg zinc a day, it has pro-dopamine effects, including increasing the binding of dopamine, and enhancing the effects of cocaine (not that i condone that).
"Zinc inhibited dopamine uptake into synaptosomes at concentrations from 0.5 to 100 microM. Zinc (0.5 and 1 microM) augmented cocaine inhibition of uptake by 58-79%. Modulation of drug binding to the dopamine uptake complex is another role for zinc in the central nervous system."
This is the end of the thread.
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