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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by SAM-e old on June 13, 2009, at 2:57:32
hello,
I started taking 400mg SAMe in the mornings and had bad anxiety, agitation and bad-memory flashbacks. I then went down to 200mg a day, now 200mg every other day. the side effect persist, though less at lower dosage/frequency.Do the side-effects I metioned eventually pass?
Or is it unlikely they will pass and I will either have to lower the dose to 100mg or 50mg ... or perhaps not take it at all as my body does not seem to like it?
SAM-e old
Posted by Sigismund on June 13, 2009, at 19:59:44
In reply to SAM-e side-fx.: anxiety+agitation - do they pass?, posted by SAM-e old on June 13, 2009, at 2:57:32
I don't know if it is a side effect. SAMe just does not suit some people. At times it has suited me, and at other times not. Most recently I felt I was better without it. And I'd guess it is unlikely to pass.
Posted by SAM-e old on June 14, 2009, at 7:28:00
In reply to Re: SAM-e side-fx.: anxiety+agitation - do they pass?, posted by Sigismund on June 13, 2009, at 19:59:44
I suppose that much can be true. do you know of any articles or studies that come to this conclusion. I have read about the low-dosage / high-dosage issue.I wonder what it is about SAMe than can cause agitation/anxiety in some people.
Posted by Sigismund on June 14, 2009, at 15:20:22
In reply to SAM-e side-fx.: anxiety+agitation - do they pass?, posted by SAM-e old on June 13, 2009, at 2:57:32
I don't have any studies. You could try lowering the dose again, or not take it. You are taking it for depression?
Posted by Sigismund on June 14, 2009, at 15:21:57
In reply to Re: SAM-e side-fx. -- ) Sigismund, posted by SAM-e old on June 14, 2009, at 7:28:00
>I wonder what it is about SAMe than can cause agitation/anxiety in some people.
I don't know. Some agitating serotonin receptor?
Posted by SAM-e old on June 15, 2009, at 4:33:36
In reply to Re: SAM-e side-fx., posted by Sigismund on June 14, 2009, at 15:21:57
I'm taking it (a) to increase my glutathion level, which is very low and (b) also for depression.
Posted by Sigismund on June 16, 2009, at 17:26:18
In reply to Re: SAM-e side-fx., posted by SAM-e old on June 15, 2009, at 4:33:36
There are other ways of increasing glutathione levels, I assume.
Would one of them be N-acetyl cysteine, taken with vit C?
Might be good for OCD (if you have that)?
Posted by SAM-e old on June 19, 2009, at 4:30:26
In reply to Re: SAM-e side-fx., posted by Sigismund on June 16, 2009, at 17:26:18
NAC is on my plan from my doctor, starting it this weekend.I dont have fullblown OCD but temporary tendencies every now and then...
I once tested SAMe with NADH and dont recall having had the side effects that I have with SAMe alone ... or NADH alone for that matter. I wonder if the two together "work together"....
Posted by Sigismund on June 19, 2009, at 18:37:09
In reply to Re: SAM-e side-fx., posted by SAM-e old on June 19, 2009, at 4:30:26
>I once tested SAMe with NADH
I have taken them both, but not together.
Posted by morganpmiller on June 24, 2009, at 11:18:33
In reply to Re: SAM-e side-fx., posted by Sigismund on June 19, 2009, at 18:37:09
Same-e will agitate many bipolars
This is the end of the thread.
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