![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Lao Tzu on November 7, 2011, at 13:11:06
I've been using pregnenolone 50mg for negative symptoms. It does help with energy and I sleep much better at night. Can't really tell if it helps with negative symptoms, but I also take 375mcg of B12 and a Centrum multivitamin with it in the afternoon, and the combination of the three has seen an improved mood, and like I said I sleep better, more restful sleep. I think I just hit on this combination by chance and it seems to work. A little caution that taking pregnenolone alone might cause some irritability, which is why I take the B12 and multivitamin with it. The irritability factor is cancelled out somewhat. At least, that's been my experience so far.
Lao
Posted by novelagent on January 12, 2012, at 17:16:02
In reply to Been trying pregnenolone 50mg per day, posted by Lao Tzu on November 7, 2011, at 13:11:06
have you also tried Vyvanse? phase II trials by Dr. Nasrallah with Shire were very encouraging (although any psychostimulant would likely replicate this).> I've been using pregnenolone 50mg for negative symptoms. It does help with energy and I sleep much better at night. Can't really tell if it helps with negative symptoms, but I also take 375mcg of B12 and a Centrum multivitamin with it in the afternoon, and the combination of the three has seen an improved mood, and like I said I sleep better, more restful sleep. I think I just hit on this combination by chance and it seems to work. A little caution that taking pregnenolone alone might cause some irritability, which is why I take the B12 and multivitamin with it. The irritability factor is cancelled out somewhat. At least, that's been my experience so far.
>
>
> Lao
Posted by novelagent on March 1, 2012, at 11:36:02
In reply to Been trying pregnenolone 50mg per day, posted by Lao Tzu on November 7, 2011, at 13:11:06
Have you tried DHEA? It's been paired a few times against in head-to-head comparisons, with similar benefit reported for negative symptoms.
Is your thinking better with it? Are you scoring higher in Lumosity.com games, perhaps? I did with DHEA, but had to stop, as it was causing me to clench my teeth, and I have a bad night guard I need to replace before I take it again.
I'm not sure if I have negative symptoms- it might just be a dependency of dexedrine, as they (avolition, anhedonia, low energy) all go away when I take dexedrine.
I'm going to take CDP Choline and glycine. Glycine's been discussed on medscape with great results by psychiatrists for negative symptoms, and my psychiatrist says it's good, but wants me to tell him before I take it...
CDP Choline was used with great success as an adjunct to galantamine in schizophrenia-- increased cognitive performance was seen, which is not seen in trials of galantamine alone for schizophrenia.
---novel
> I've been using pregnenolone 50mg for negative symptoms. It does help with energy and I sleep much better at night. Can't really tell if it helps with negative symptoms, but I also take 375mcg of B12 and a Centrum multivitamin with it in the afternoon, and the combination of the three has seen an improved mood, and like I said I sleep better, more restful sleep. I think I just hit on this combination by chance and it seems to work. A little caution that taking pregnenolone alone might cause some irritability, which is why I take the B12 and multivitamin with it. The irritability factor is cancelled out somewhat. At least, that's been my experience so far.
>
>
> Lao
Posted by Lao Tzu on March 11, 2012, at 12:05:13
In reply to Re: Been trying pregnenolone 50mg per day » Lao Tzu, posted by novelagent on March 1, 2012, at 11:36:02
Thanks for your post. I didn't get the same benefit from DHEA as from pregnenolone. Second, I don't respond well to glycine. It actually makes my depression worse, so I am not a good candidate for glycine therapy. I take some fish oil everyday, and that is also supposed to be great for brain function in schizophrenia. Also, I don't think my doctor would prescribe dexedrine to me. It's not front-line therapy, but it is interesting how well that works for you. Honestly, I could use a little more stimulation. The drug cocktail I take can be pretty sedating, Zoloft, Lamictal, and Risperdal. It just takes a lot out of you, but then again, maybe it's just a symptom of the illness. I've always been a low energy person except for my childhood years. I try to rely on various vitamins to amp up my energy, including the pregnenolone, multivitamin, B vitamins, a good amount of protein in the diet, and a little coffee, but not much. Too much caffeine actually does the opposite to me. It makes me lethargic. That's weird, but it happens anytime I go crazy with the coffee. Wish it weren't so. I always like a good coffee buzz. Again, thanks for your response. Stay well!
Lao
This is the end of the thread.
Psycho-Babble Alternative | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.