Psycho-Babble Alternative Thread 1080810

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Resveratrol?

Posted by SLS on July 28, 2015, at 7:26:50

Can anyone comment on the use of Resveratrol? I am being treated for bipolar depression.

Technically, I would like to increase my levels of intracellular cAMP by inhibiting PDE4. Resveratrol is supposed to do this.

- Scott

Re: Resveratrol?

Posted by Christ_empowered on September 1, 2015, at 5:59:03

In reply to Resveratrol?, posted by SLS on July 28, 2015, at 7:26:50

hi. I've never heard of resveratrol being used for low mood, but...kinda makes sense. Seems like antioxidants help all kindsa crazy, from depression to psychosis.

My own approach to supplements, because of my fondness for Orthomolecular, is to go high dose for a while before drawing any conclusions. Also, taking a couple supplements together can often lead to better results than just 1 or 2. I don't know about Resveratrol, but grape seed extract is often taken w/ green tea extract, for example.

Hope it works out for you.

Re: Resveratrol?

Posted by SLS on September 9, 2015, at 7:19:33

In reply to Re: Resveratrol?, posted by Christ_empowered on September 1, 2015, at 5:59:03

> hi. I've never heard of resveratrol being used for low mood, but...kinda makes sense. Seems like antioxidants help all kindsa crazy, from depression to psychosis.
>
> My own approach to supplements, because of my fondness for Orthomolecular, is to go high dose for a while before drawing any conclusions. Also, taking a couple supplements together can often lead to better results than just 1 or 2. I don't know about Resveratrol, but grape seed extract is often taken w/ green tea extract, for example.
>
> Hope it works out for you.

Thanks. I appreciate your support and input. There is much about orthomolecular psychiatry that I am clueless about.

My interest in resveratrol lies in its reported ability to inhibit PDE4 (phosphodiesterase type 4). Inhibition of this enzyme increases the amount of cytosolic (cell fluid) cAMP (cyclic adenosine monophosphate). cAMP acts in neurons as a "second messenger", and participates in a cascade of events that lead to changes in gene transcription. In other words, resveratrol can act as a mood modulator.

- Scott

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