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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by James H on April 29, 2011, at 16:48:05
Will this combo cause serotonin syndrome? I know Geodon has some serotonin-reuptake properties. I'm taking Parnate and am considering Geodon. I called Walgreen's and the pharmacist said she didn't see any interaction. However, I don't trust modern databases when it comes to old MAOI's. I've heard a lot of erroneous or outdated information from a host of sources.
JameH
Posted by desolationrower on May 1, 2011, at 17:24:35
In reply to irreversible MAOI + Geodon safe?, posted by James H on April 29, 2011, at 16:48:05
based on binding, I would say yes, it should actually prevent 5ht syndrome. Of course, i haven't seen any actual testing, so it isn't as confirmed to be safe as something like nortriptyline that has human in vivo testing.
-d/r
Posted by SLS on May 15, 2011, at 6:34:31
In reply to Re: irreversible MAOI + Geodon safe?, posted by desolationrower on May 1, 2011, at 17:24:35
> based on binding, I would say yes, it should actually prevent 5ht syndrome. Of course, i haven't seen any actual testing, so it isn't as confirmed to be safe as something like nortriptyline that has human in vivo testing.
>
> -d/r
I had been on Nardil and Geodon for about a month without sequalae (untoward consequences). I discontinued Geodon for lack of efficacy.It is interesting that Geodon might reduce the risk of serotonin syndrome. What are the mechanisms by which this may occur (even if theoretical)?
Thanks.
- Scott
Posted by desolationrower on June 5, 2011, at 17:01:20
In reply to Re: irreversible MAOI + Geodon safe? » desolationrower, posted by SLS on May 15, 2011, at 6:34:31
> > based on binding, I would say yes, it should actually prevent 5ht syndrome. Of course, i haven't seen any actual testing, so it isn't as confirmed to be safe as something like nortriptyline that has human in vivo testing.
> >
> > -d/r
>
>
> I had been on Nardil and Geodon for about a month without sequalae (untoward consequences). I discontinued Geodon for lack of efficacy.
>
> It is interesting that Geodon might reduce the risk of serotonin syndrome. What are the mechanisms by which this may occur (even if theoretical)?
>
> Thanks.
>
>
> - ScottJust that like many 2nd gen antipsychotics, its a potent antagonist of h5t2a/c receptors.
-d/r
This is the end of the thread.
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