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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 20 of 20. This is the beginning of the thread.
Posted by BekkaH on November 27, 2002, at 0:35:21
I just read on another Internet message board that Atomoxetine has just been approved by the FDA. It will be available some time in early 2003 under the proprietary name "Strateera." It is a norepinephrine reuptake inhibitor, similar to reboxetine. It is not a stimulant and will not be a restricted drug. Although I believe it is an antidepressant, it will be marketed as an ADD drug.
Posted by BekkaH on November 27, 2002, at 1:18:13
In reply to Atomoxetine, posted by BekkaH on November 27, 2002, at 0:35:21
I think I spelled the brand name incorrectly in the previous post. According to the AP Press release, the brand name for Atomoxetine is Strattera.
Posted by 3 Beer Effect on November 27, 2002, at 3:29:34
In reply to Atomoxetine, posted by BekkaH on November 27, 2002, at 0:35:21
Posted by rytoor on November 27, 2002, at 19:32:30
In reply to (atomoxetine hcl) Strattera- FDA approved for ADD, posted by 3 Beer Effect on November 27, 2002, at 3:29:34
I'm wondering why this hasn't received more attention. Is it like Reboxetine and Desipramine in being NE targeted? I wonder why Lilly isn't touting it for depression, too. Thoughts?
R
Posted by BekkaH on November 27, 2002, at 20:21:58
In reply to Re: (atomoxetine hcl) Strattera- FDA approved for ADD, posted by rytoor on November 27, 2002, at 19:32:30
> I'm wondering why this hasn't received more attention. Is it like Reboxetine and Desipramine in being NE targeted? I wonder why Lilly isn't touting it for depression, too. Thoughts?
>
***********************************************I've read that Atomoxetine is similar to reboxetine. They are both NE reuptake inhibitors, but I do not understand why Lilly wouldn't be marketing it for depression as well. Perhaps doing so would take longer for FDA approval?
Posted by utopizen on November 29, 2002, at 20:57:02
In reply to Strattera- FDA approved for ADD -rytoor, posted by BekkaH on November 27, 2002, at 20:21:58
Call me a cynic, and a grumpy one at that, but this could do to the amphetamines what benzos did to the barbs-- make it so very few doctors end up prescribing amphetamines, so those remaining patients who prefer it or only respond to it will have a tough time getting it as the narrowing scope of amphetamine sales allow the DEA to zone in the few remaining doctors who primarily end up treating it.
Or it could just be used now and then when docs can get away it with... I'm not good at predicting. Sure ,it might work on me, but I'm doubtful as well as Adderall or Dex does. Amphetamines will always remain the gold standard, even if it becomes like saying "Seconal" or something 10 years from now to ask for it.
Posted by viridis on November 29, 2002, at 22:02:35
In reply to Re: Strattera- FDA approved for ADD -rytoor, posted by utopizen on November 29, 2002, at 20:57:02
Why don't you try it first and see how it works before speculating? That's my plan. Things are always improving, although I agree that amphetamines are very effective for ADD (and depression).
P.S. benzos really are better than barbs for most, so maybe this will be similar?
Posted by utopizen on November 30, 2002, at 15:14:51
In reply to Re: Strattera- FDA approved for ADD -rytoor, posted by viridis on November 29, 2002, at 22:02:35
> Why don't you try it first and see how it works before speculating? That's my plan. Things are always improving, although I agree that amphetamines are very effective for ADD (and depression).
>
> P.S. benzos really are better than barbs for most, so maybe this will be similar?
>
minus the ability to use it to do an all-nighter...
Posted by SLS on December 1, 2002, at 0:50:56
In reply to Re: Strattera- FDA approved for ADD -rytoor, posted by utopizen on November 30, 2002, at 15:14:51
Atomoxetine was originally named tomoxetine and was first developed as an antidepressant. It will probably make a good one too. However, Eli Lilly realized that it could launch a coup over the rest of the pharmaceutical industry by getting it approved as the first non-controlled, non-stimulant treatment for ADD/ADHD. Atomoxetine is probably nothing like reboxetine, a drug that I think is generally inferior to the majority of antidepressants. Atomoxetine should be a great tool for depression, even if only as an adjunct.
- Scott
Posted by Ritch on December 1, 2002, at 10:19:11
In reply to Re: Strattera- FDA approved for ADD -rytoor, posted by SLS on December 1, 2002, at 0:50:56
> Atomoxetine was originally named tomoxetine and was first developed as an antidepressant. It will probably make a good one too. However, Eli Lilly realized that it could launch a coup over the rest of the pharmaceutical industry by getting it approved as the first non-controlled, non-stimulant treatment for ADD/ADHD. Atomoxetine is probably nothing like reboxetine, a drug that I think is generally inferior to the majority of antidepressants. Atomoxetine should be a great tool for depression, even if only as an adjunct.
>
>
> - ScottScott, I will be checking into that one when it becomes available for sure. Desipramine worked as good (or better) than stimulants for my ADHD symptoms previously, but I couldn't tolerate the postural hypotension, tachycardia, and blurry vision from it. It would be interesting to see what the most common discontinuation symptoms are and how it differs from reboxetine.
Posted by Moe Larry on December 3, 2002, at 21:57:41
In reply to Re: Strattera- FDA approved for ADD -rytoor, posted by utopizen on November 30, 2002, at 15:14:51
One can find complete information, including the "package insert" here: http://www.Strattera.com
Earliest published tomoxetine literature is 1985. A cynic suggested that Lilly envisioned greater sales and perhaps longer patent life with an ADD drug instead of another antidepressant.
Posted by Ritch on December 4, 2002, at 9:05:57
In reply to Re: Strattera- FDA approved for ADD -rytoor, posted by Moe Larry on December 3, 2002, at 21:57:41
> One can find complete information, including the "package insert" here: http://www.Strattera.com
>
> Earliest published tomoxetine literature is 1985. A cynic suggested that Lilly envisioned greater sales and perhaps longer patent life with an ADD drug instead of another antidepressant.Thanks for that link, got the monograph and read it through. I like the short half-life (for sleep) and low discontinuation rate. It shouldn't interact with the little bit of Effexor I take, my primary concern will be with diastolic blood pressure (I tend to get that easily with NE meds).
Posted by SLS on December 9, 2002, at 9:49:35
In reply to Re: Strattera- FDA approved for ADD -rytoor » Moe Larry, posted by Ritch on December 4, 2002, at 9:05:57
Hi Mitch.
> Thanks for that link, got the monograph and read it through.Where can I find the monograph?
Thanks.
- Scott
Posted by Ritch on December 10, 2002, at 16:40:25
In reply to Re: Strattera- FDA approved for ADD -rytoor » Ritch, posted by SLS on December 9, 2002, at 9:49:35
> Hi Mitch.
>
> > Thanks for that link, got the monograph and read it through.
>
> Where can I find the monograph?
>
> Thanks.
>
>
> - Scott
>Hi Scott, this should get you there:
http://www.strattera.com/cnt_common/info_pi.html
Posted by Vince on December 12, 2002, at 17:00:16
In reply to Re: Strattera- FDA approved for ADD -rytoor » SLS, posted by Ritch on December 10, 2002, at 16:40:25
Posted by Ritch on December 12, 2002, at 23:32:43
In reply to When will Strattera be in pharmacies? (nm), posted by Vince on December 12, 2002, at 17:00:16
Posted by Alastar on January 8, 2003, at 11:00:39
In reply to Correction: Strattera = Atomoxetine, posted by BekkaH on November 27, 2002, at 1:18:13
Will this new drug alleviate tics caused by the stimulants?
Posted by Ritch on January 8, 2003, at 23:08:06
In reply to Re: Strattera and Tics, posted by Alastar on January 8, 2003, at 11:00:39
> Will this new drug alleviate tics caused by the stimulants?
That would be difficult to say since med induced tics tends to be highly individual. I got tics from Adderall and Focalin (esp.) which were dose-related. Even with nortriptyline I noticed that I would stutter slightly from time to time. All you can do for sure is just try the med and see what happens. Start at lower doses and work your way up.
Posted by avid abulia on June 17, 2003, at 10:34:11
In reply to Re: Strattera and Tics » Alastar, posted by Ritch on January 8, 2003, at 23:08:06
> > Will this new drug alleviate tics caused by the stimulants?
>
> That would be difficult to say since med induced tics tends to be highly individual. I got tics from Adderall and Focalin (esp.) which were dose-related. Even with nortriptyline I noticed that I would stutter slightly from time to time. All you can do for sure is just try the med and see what happens. Start at lower doses and work your way up.i have tourette's syndrome, and when i took strattera (despite starting at a full-sized dose, and being a poor metabolizer of several cyp 450 isozymes, including the one that metabolizes strattera, i didn`t tic *much* more, as compared to say, tegretal, where i ticced like crazy, developed myoclonus, and in general felt like i was that close *holds fingers a millimeter or so apart* to checking out...
though, on tegretal all i could do was sleep, and i would have obscene monologues out loud in my sleep, whereas, with strattera, i just didn't sleep for three days and told obscene jokes only in appropriate times.
~AA
Posted by luv2healwounds on September 6, 2003, at 9:39:20
In reply to Atomoxetine, posted by BekkaH on November 27, 2002, at 0:35:21
I can only say that I have been on Strateera for a week and it has been great. I have ADHD as an adult and have been using caffeine and diet pills to get me thru the years. If anyone wants to talk I would love to. This is all new for me with the medication and I do wound care for gosh sakes! I am confused on how this is working as a nonstimulant medication and I needed the stimulants before to make me feel ok. Cheryl
luv2healwounds@aol.com
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