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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 18 of 18. This is the beginning of the thread.
Posted by Neo on February 10, 2003, at 11:23:20
Hi,
I'm no respondent to every classic AD on the market (i was on everyone of them).
Now i've read wonder about Nardil (IMAO) but it is not available in my country (europe).
In my country is available Parnate (tranilcypromine) another Imao, but i do not know if it could be an effective substitute of Nardil.
Somebody of you has an experience?
Thanx very much for your help!
Bye
Posted by cosis on February 10, 2003, at 11:59:46
In reply to PARNATE is effective like NARDIL?, posted by Neo on February 10, 2003, at 11:23:20
Yes they are both very effective drugs, good things are said about both drugs. I have only tried Nardil :)
My doc said Parnate had more of a reputation for Depression and Nardil for Socal Anxiety, but I am sure they both work on both problems
Posted by MelD on February 10, 2003, at 18:16:32
In reply to Re: PARNATE is effective like NARDIL?, posted by cosis on February 10, 2003, at 11:59:46
I found Parnate to be quick and effective in treating my atypical depression and would recommend it. Good luck and hope it works for you!
Posted by missliz on February 11, 2003, at 0:30:52
In reply to Re: PARNATE is effective like NARDIL?, posted by MelD on February 10, 2003, at 18:16:32
I've been on both, and both work well for depression and social anxiety. Nardil has a reputation of being kind of sedating, but I loved it. Took up bike racing, lost weight, got a degree. Parnate can be a rough ride on, it rewires your brain, but if you can hold out for the first eight weeks it's great. The problem is that it metabolizes into all sorts of weird stuff, including amphetemine and methamphetamine. It can be VERY hard to sleep enough for the first few weeks. It can also make you tacchycardic and can cause cardiac arrythmia- rare, but it happened to me. I think it was dose related. It's well worth the diet and drug restrictions if it works, and I understand it always works. Just go up slowly on the dose, you have to be psychologicly ready to be well when you take Parnate and being well can be a big surprise.
Bonne chancemissliz
Posted by ace on February 11, 2003, at 19:03:27
In reply to Re: PARNATE is effective like NARDIL?, posted by missliz on February 11, 2003, at 0:30:52
> I've been on both, and both work well for depression and social anxiety. Nardil has a reputation of being kind of sedating, but I loved it. Took up bike racing, lost weight, got a degree. Parnate can be a rough ride on, it rewires your brain, but if you can hold out for the first eight weeks it's great. The problem is that it metabolizes into all sorts of weird stuff, including amphetemine and methamphetamine. It can be VERY hard to sleep enough for the first few weeks. It can also make you tacchycardic and can cause cardiac arrythmia- rare, but it happened to me. I think it was dose related. It's well worth the diet and drug restrictions if it works, and I understand it always works. Just go up slowly on the dose, you have to be psychologicly ready to be well when you take Parnate and being well can be a big surprise.
> Bonne chance
>
> missliz
Hey MissLiz!,Are you the old 'Elizabeth' from this site? If so, your posts were great.
Also, I saw you on the neurology boards defending the MAOIs -- GREAT WORK! I backed you up 100% in one of thoses threads. You don't go their anymore? We should travel across and bring on the MAOI talk!!!
Ace,
Nardil, 90mg.
Posted by JeffH on February 12, 2003, at 21:55:44
In reply to PARNATE is effective like NARDIL?, posted by Neo on February 10, 2003, at 11:23:20
Parnate is beautiful, baby! Did the trick after many years of suffering.
When it first began to work, I felt that I would kill any soul who might try to steal my Parnate.
Why wasn't it prescribed during my long years of suffering? My doc, who works at a major university, uses me as an example when working with residents. In certain cases, he is using it as a first-line med rather than a last resort hope.
Posted by Jack Smith on February 13, 2003, at 12:06:58
In reply to Re: PARNATE is effective like NARDIL?, posted by JeffH on February 12, 2003, at 21:55:44
Jeff,
Your story is great, I too am going to begin parnate in a few weeks, I am keeping my fingers crossed that this med will be the one for me. What are your symptoms?
How long have you been on it?
What is your dose?Also, there is an MAOI YahooGroup that could really use an experienced user such as yourself, please join it if you have not already.
http://groups.yahoo.com/group/maois/
People like you could really help those who are just starting out.
Thank you,
Jack
Posted by jsarirose on February 13, 2003, at 15:45:20
In reply to Re: PARNATE is effective like NARDIL? » JeffH, posted by Jack Smith on February 13, 2003, at 12:06:58
> Jeff,
>
> Your story is great, I too am going to begin parnate in a few weeks, I am keeping my fingers crossed that this med will be the one for me. What are your symptoms?
> How long have you been on it?
> What is your dose?
>
> Also, there is an MAOI YahooGroup that could really use an experienced user such as yourself, please join it if you have not already.
>
> http://groups.yahoo.com/group/maois/
>
> People like you could really help those who are just starting out.
>
> Thank you,
>
> JackI'm a little late joining the conversation, but I wanted to echo having great results with Parnate. I tried just about every drug under the sun over the last 15 years. Finally we got to the MAOI's which always seem to be a last resort. I started with Parnate since I had some weight problems and Parnate doesn't promote weight gain (and can help with weight loss).
I've been on it for over a year. I took up to 100mg at one point, tapered down to 60mg to see if I was okay with it. We stayed at 60mg and added Lamictal (we'd added a few others that didn't work). The idea was that perhaps if I went up to a high enough dose on Lamictal (perhaps 800mg) I could go off Parnate. But I haven't had any effect so far and I'm going up on Parnate again. I'm aiming for 80mg this time.
But - Parnate has helped me keep a part-time job for a year now (quite rare for me). And to actually date, and seek therapy again.
-Jessica
ps - I've done a ton of research about the diet restrictions, so I think I'll join the yahoo group and see if I can help anyone.
Posted by Neo on February 14, 2003, at 12:56:11
In reply to Re: PARNATE is effective like NARDIL?, posted by jsarirose on February 13, 2003, at 15:45:20
Hi,
after years of reading up and down this board i realized that classic AD work about 50% times.
This is the why this board is full of switches: switches from effexor to paxil, to zoloft, from prozac to lexapro, from celexa to any other kind of AD and so on.
The thing i noticed is that, when people are on MAOI they feel pretty well, seem to be renewed and returned to life: i've never read: "Nardil killed me!" or "I can't stand Parnate!" or "Maoi was ineffective at all!".
My question is this: I failed to read this board or maoi are effective in the most part of people, in particular in non-respondent depression?
And if they work almost everytime, why they are used only in a small part of people?
Perhaps cause they food limitation or side effects?
Truly, i've never read "nardil make me dizzy and drowsy" but i've read it thousand times about SSRI!
There is something that i had misunderstood?
Please help me to understand!
Thanx to all!!
Posted by Jack Smith on February 14, 2003, at 13:36:12
In reply to MAOI works 100% cases???? or not??, posted by Neo on February 14, 2003, at 12:56:11
I too have been incredibly impressed by what people say about MAOI's. If you do a search across the internet, you will rarely hear someone say that an MAOI flat out didn't work. YOu will hear that people had to stop them for one reason or another but they do seem to be incredibly effective.
I think the reason they are not prescribed so much is two-fold. First, with all the advent of prozac and its cousins and newer AD's, psychiatrists felt for a few years that they had found a cure to depression. Soon, however, it was realized that these anti-d's are only as effective as TCA's albeit with fewer side effects (usually). So, many doctors were not trained at all with MAOI's. Also, with prozac came other doctors willing to prescribe anti-d's, this was very rare prior to the late '80's as psychiatric drugs were considered to be only for use by psychiatrists. So, more people get their ad's by GPs and ob-gyn's who would never think of prescribing an MAOI.
The second reason why they are not prescribed is pretty obvious--why not try other ad's that do not have so many food and drug interactions. One of the best thing about the newer ad's (esp. zoloft and celexa) is that they hardly interact with anything.
Just my two cents on the subject
JACK
Posted by kara lynne on February 14, 2003, at 14:05:05
In reply to MAOI works 100% cases???? or not??, posted by Neo on February 14, 2003, at 12:56:11
It seems like doctors for the most part like to rely on newer drugs and SSRI's in favor of MAOI'S. I guess that's due largely to the fact that (although some people claim this risk is overstated) fatal hypertensive situations can occur when you mix MAOI's with certain foods. SSRI's don't have those complications, but they are far less efffective for refractory depression. My doctor says for those cases MAOI's and tricyclics are far and away more effective. Tricyclics worked for me, but had dangerous side effects. Nardil, by the way, made me dizzy and nauseaus and I couldn't finish out the trial period. Many people have stopped Nardil because of cetain intolerable side effects (edema, dizzyness, weight gain), but as you read, when it works, it seems to work wonders.
Posted by stjames on February 14, 2003, at 14:46:28
In reply to MAOI works 100% cases???? or not??, posted by Neo on February 14, 2003, at 12:56:11
> Hi,
> after years of reading up and down this board i realized that classic AD work about 50% times.
This board in no way represents the true %
of sucess or failure of any AD in the general population. Only a properlly conducted study can do that. This boadr is in now wat that kind of study.
Posted by ayrity on February 15, 2003, at 17:27:45
In reply to MAOI works 100% cases???? or not??, posted by Neo on February 14, 2003, at 12:56:11
I tried Moclobomide and Parnate- they did nothing for me. :-(
Posted by Peter S. on February 15, 2003, at 19:11:15
In reply to MAOI works 100% cases???? or not??, posted by Neo on February 14, 2003, at 12:56:11
I have tried both Nardil and Parnate at very high doses. Parnate worked for a short time and then faded out. Nardil didn't seem to do anything.
> Hi,
> after years of reading up and down this board i realized that classic AD work about 50% times.
> This is the why this board is full of switches: switches from effexor to paxil, to zoloft, from prozac to lexapro, from celexa to any other kind of AD and so on.
> The thing i noticed is that, when people are on MAOI they feel pretty well, seem to be renewed and returned to life: i've never read: "Nardil killed me!" or "I can't stand Parnate!" or "Maoi was ineffective at all!".
> My question is this: I failed to read this board or maoi are effective in the most part of people, in particular in non-respondent depression?
> And if they work almost everytime, why they are used only in a small part of people?
> Perhaps cause they food limitation or side effects?
> Truly, i've never read "nardil make me dizzy and drowsy" but i've read it thousand times about SSRI!
> There is something that i had misunderstood?
> Please help me to understand!
> Thanx to all!!
Posted by JeffH on February 15, 2003, at 22:57:58
In reply to Re: PARNATE is effective like NARDIL? » JeffH, posted by Jack Smith on February 13, 2003, at 12:06:58
Jack:
Good luck and thanks for the congratulations.
I'm on a 100mg Parnate, which seems like a lot, but I'm a big man. This was the dosage that worked for me -- all at once in the morning. My doc and I played with the dosage, splitting it between morning and evening, etc.
I'm also on Lamictal. Dosage? At the risk of looking ignorant, let me say that it's one big, blue, odd-shaped pill in the morning.
I'm also big on fish oil. I've been on it half a year, and I believe that it's boosted the effectiveness of the medicine.
One last note: My diet seems have a big effect. When I cheat and have a little cheese pepperoni, I feel that I have a low-grade headache the following day. Smoking seems to hurt, too.
Good luck and long live Parnate,
Jeff
Posted by LUKA62 on February 17, 2003, at 0:28:05
In reply to MAOI works 100% cases???? or not??, posted by Neo on February 14, 2003, at 12:56:11
Nardil has affected me in different ways over the years along with being a very effective AD for me. The biggest problem I had [ the headache or even chest pain if I cheated on the diet notwithsatanding] for the longest time was related to low blood pressure. It stayed quite low, at one point it stayed around 74/40 (yes 74/40.) I was lightheaded a great deal of the time. Also it has caused hypomania or mania.
Posted by Peter S. on February 17, 2003, at 13:17:16
In reply to Re: PARNATE is effective like NARDIL?, posted by JeffH on February 15, 2003, at 22:57:58
Hi Jeff,
Glad to hear things are working for you. How much fish oil are you taking per day? What brand and where do you get it? I've tried Eskimo 3 but the cost is beyond my means.
Thanks!
Peter
> Jack:
>
> Good luck and thanks for the congratulations.
>
> I'm on a 100mg Parnate, which seems like a lot, but I'm a big man. This was the dosage that worked for me -- all at once in the morning. My doc and I played with the dosage, splitting it between morning and evening, etc.
>
> I'm also on Lamictal. Dosage? At the risk of looking ignorant, let me say that it's one big, blue, odd-shaped pill in the morning.
>
> I'm also big on fish oil. I've been on it half a year, and I believe that it's boosted the effectiveness of the medicine.
>
> One last note: My diet seems have a big effect. When I cheat and have a little cheese pepperoni, I feel that I have a low-grade headache the following day. Smoking seems to hurt, too.
>
> Good luck and long live Parnate,
>
> Jeff
Posted by jewels52 on November 11, 2003, at 17:14:33
In reply to Re: MAOI works 100% cases?side effects » Neo, posted by LUKA62 on February 17, 2003, at 0:28:05
i was on nardil for 6 months for severe social phobia and depression....i gained 30 pds and felt that it was starting to poop out...so decided to give a stimulant plus and benzo i try...i have donr terrible on this...and just stopped taking the adderall today. my dr called in parnate to give a try tommorrow...is it to soon to take parnate if adderall is still in my system???
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