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Re: Naltrexone

Posted by Elizabeth on December 14, 1998, at 3:15:31

In reply to Re: Naltrexone, posted by ian on September 12, 1998, at 11:46:25

> Do a search of RxQx on this site and you'll find a number of items from MDs supporting the use of naltrexone as an antidepressant. It appears that it does indeed work for some people.

My impression is that naltrexone is primarily for augmentation of antidepressants when there is a partial response (or preventing poop-out, or jump-starting if poop-out has already occurred) as well as for substance dependence (especially opiates and alcohol). It is also used for people with chronic self-injury problems (e.g., cutting). But I don't know how good it would be by itself for straightforward depression.

Also, I asked a psychopharmacologist who I have seen for consultations a few times (Alexander Bodkin, at McLean) about naltrexone, and he said that he'd found that people tend to experience dysphoria when they're on it - "it's not a pleasant drug to be taking."

Is there a reason you're interested in naltrexone in particular?


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poster:Elizabeth thread:165
URL: http://www.dr-bob.org/babble/19981201/msgs/1569.html