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Re: Seamus Nardil vs. Parnate redux

Posted by Seamus on June 11, 1999, at 10:35:28

In reply to Re: Seamus Nardil vs. Parnate, posted by Seamus on June 11, 1999, at 10:19:57

Damn thing ate most of my reply. I'll try once more...

>>Do you find your libido is strong with Parnate, neutral, or dead?
Same as it ever was. The trick to Parnate is consistency: the same doses, the same time of day. Libido may increase if you cut the dose due to (I assume) some sort of cholinergic rebound. But you don't want to do that because the AD effect wanes just as quickly.

>will I lose sexual interest? Nah
>Has Parnate done that to you? Nah

>How does Parnate compare to Nardil in other aspects besides sexual?
Onset of action is a week or less. Stimulating side effect 2 hrs post dosing; caffeine can make this much worse. (I have a startle reflex from Hell) No constipation, urinary hesitancy or carbo cravings. Tyramine reaction much more noticeable, but your mileage may vary.

>Same relief from depression?
Same relief, but the quality differs. I recall I was more "content" on Nardil, but on Parnate my drive is higher. I sleep less, too.

> Are you more hyper/anxious on Parnate?
I'm very consistent w/ my dosing so I can't really tell. I think I'm pretty hyper to begin with. I'll take 0.025 -- 0.5 mg Xanax if I get really jumpy.

>Any wieght gain with either drug?<<
Not per se, because of the anorectic properites of Parnate I've developed a nasty habit of going for quick calories when I absolutely have to eat. That or the onset middle age (I'm 38) has added fifteen pounds or so over the course of the last three years.

Seamus


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