Posted by Annie on August 16, 1999, at 22:07:01
In reply to Re: Selegiline for depression?Annie, posted by Adam on August 16, 1999, at 17:02:35
Adam
I was in the double blind study first (no improvement for me), then went into the open label 30mg. The initial symptoms were greatly increased anxiety and urinary urgency. I'd be in the middle of a sentence and suddenly have to run like mad to the closest 'facility'. Oh yes I had a little blurry vision. These went away and constipation was the only physical side effect and it wasn't horrible. My word retrieval on Selegiline was absolutely terrible. I couldn't remember the name of common objects. The good part was that my metabolism kicked in and I started to lose weight effortlessly. My reaction to stress improved dramatically and I stopped having suicidal ideations. My energy level increased but then seemed to level out. The anhedonia remained, but I felt like I was in heaven compared to where I had been for years. I hope they have a dosage higher than 30 mg because I would return to the patch in an instant if it were available now. I hope it is as good for you -or even better!
Annie> Hey, Annie,
>
> I was wondering, what sort of side effects did you experience on
> selegiline? I think I may be experiencing mild, um, difficulties.
>
> If that's all I get out of this, I'll be a dissappointed guy. I'll
> try and hang in there, though. For the past couple months I've been
> doing OK, if a bit anhedonic, and to have some real depressive symptoms
> come back has been a frightening experience. One thing I hoped for
> was this super-quick onset of antidepressant effect that the patch
> system was supposed to deliver. If I'm on the drug, I'm not seeing it,
> that's for damn sure. If I had to make a guess, this stuff might be
> aggravating things. I wish I knew for sure.
>
> Ah, the joys of double-blinded clinical trials...the open label segment
> is five weeks away. Yikes!
>
> > Hang in there Adam! I finished a patch study 8 days ago. I felt worse until week 5 or 6 and then it kicked in! I'm sorry the study is over. It was my first depression break in years.
> > Annie
> >
> > > For anyone who is curious:
> > >
> > > I have been involved with the transdermal selegiline study for about 2 1/2 weeks now.
> > > I have experienced no benefit whatsoever, and a slight decline in my mood. Side effects
> > > seem to be minimal. I'm having a little trouble sleeping, but this has always been a
> > > problem with me, and not that I'm off Remeron, I wouldn't expect to be sleeping as well.
> > >
> > > It may be that I'm on placebo. Time will tell.
> > >
> > >
> > >
> > > > Has anyone heard of selegiline for depression. I have heard that it can be helpful.
poster:Annie
thread:5905
URL: http://www.dr-bob.org/babble/19991001/msgs/10209.html