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Re: Are Benzodiazepines Like Alcohol?

Posted by Phillip Marx on January 1, 2000, at 16:08:40

In reply to Re: Are Benzodiazepines Like Alcohol?, posted by Scott L. Schofield on January 1, 2000, at 10:30:54

Thanks Scott. That helps.

Hmmmm. Disinhibition explains me to me.

When going to sleep, I have only a half hour or so of “disinhibition” that enables me to write. Un-re-written brainstorming can sound like a storming brain. My higher perfection-control circuits seem to go to sleep first. I suspect that last taught/learned (end-stage training) neurons are less mature and more susceptible biochemically than the so-called primal neuron areas. Those early-life activated neurons may even be significantly geometrically larger and require a much higher external serum concentration of a given medication to achieve the same internal cell concentration or un-defended effect. They sure have a more developed and cross-referenced dendrite and axon temporal advantage. Maybe there’s a membrane surface area scale efficiency effect or age-related permeability curve. Sleep, no longer instantaneous for me, seems PROGRESSIVELY effective against higher (later-life) developed functions first with me. I’ve told several people it feels like truth serum. I don’t drink, so I didn’t think of an alcohol-bartender type dump before.

I also lose the inhibition against writing sloppy and contain (constrain) my thinking to the subject at hand. This lets me write more, which gets out more, but does go on and on uninhibited (disinhibited). Indeed, the freedom is jealous of its freedom and averse to superficial inhibition constraint.

I normally multi-process (multi-thread) as much as possible, not as much as moms, but I do imitate that. I have never been jealous of monotonic thinking anyway. Life doesn’t have to be colorless, lifeless or music-free.

The known deadline of eminent sleep has trained me to force me to decline time-robbing structural control and recursive editing, else my completion-manias will kick in worse. Thus, I sacrifice structure for content since I abhor structure without content. Anyone can put all the pieces together if all the pieces are all there. No one can put all the pieces together if all the pieces aren’t all there.

Can mere disinhibition be read as mania? Especially when most disinhibited at end-stage sleep onset near conk-out? Non-sleep is presumed manic. Is it oxymoronic to think that sleep-onset is manic-like too? If I only write when I am at my worst, then do all the derivative impressions get an honest impression?

Sleep offset is the reverse sequence. I was up late before medicating since I didn’t wish to be unconscious if I needed to be awake. As soon as the rambling wears off, so does the writing inclination. Sense might be nonlinearly inversely proportional to non-sense.

pm
hmmm. Date=000101 military. Binary 666 gag opportunity?

> When I drink I feel so happy and uninhibited by anxiety, especially social anxiety. I know this is normal, but is that what benzos like Valium, Klonopin and Xanax make you feel like? If so, then they're the drug for me. How's this analogy, Benzo:Alcohol::SSRI:Marijuana ?
I just wanted to add one thing to this thread.
Both alcohol and benzodiazepines are capable of producing behavioral “disinhibition”. Disinhibition is basically the shutting-down of those neural pathways that would otherwise serve to help control one’s emotions and behaviors. I believe it is the inhibition of the inhibition neurons (thus disinhibition) that allows one to feel less inhibited in social situations. This alone may reduce anxiety, as there would be less cognitive dissonance to create it. This reduction in anxiety may be synergistic with the other anti-anxiety properties these drugs may have.
Disinhibition can be dangerous. It can cause an otherwise docile person to become violent. Perhaps this is the reason some people get loud or truculent when they drink, regardless of what is going on around them. In those infrequent occurrences of benzodiazepine-induced disinhibition, the magnitude of the behavioral effects can be much greater.

- Scott

> > When I drink I feel so happy and uninhibited by anxiety, especially social anxiety. I know this is normal, but is that what benzos like Valium, Klonopin and Xanax make you feel like? If so, then they're the drug for me. How's this analogy, Benzo:Alcohol::SSRI:Marijuana ?
>
> I just wanted to add one thing to this thread.
>
> Both alcohol and benzodiazepines are capable of producing behavioral “disinhibition”. Disinhibition is basically the shutting-down of those neural pathways that would otherwise serve to help control one’s emotions and behaviors. I believe it is the inhibition of the inhibition neurons (thus disinhibition) that allows one to feel less inhibited in social situations. This alone may reduce anxiety, as there would be less cognitive dissonance to create it. This reduction in anxiety may be synergistic with the other anti-anxiety properties these drugs may have.
>
> Disinhibition can be dangerous. It can cause an otherwise docile person to become violent. Perhaps this is the reason some people get loud or truculent when they drink, regardless of what is going on around them. In those infrequent occurrences of benzodiazepine-induced disinhibition, the magnitude of the behavioral effects can be much greater.
>
>
> - Scott


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