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Re: dysthymia & meds - Anyone else ?

Posted by Scott L. Schofield on January 21, 2000, at 10:35:26

In reply to dysthymia & meds, posted by dysthymia on January 19, 2000, at 12:02:24


> For me, wellbutrin sr did nothing - all the way up to 200mg twice daily.

> Now trying effexor xr. Helps me some w/concentration & being a bit more out-going/sociable, but I'm still low on energy/motivation. Also makes me sleepy. Was taking 75mg/day, now trying 150mg/day.

I know of someone with dysthymia who has had success with a combination of Effexor (venlafaxin) and Wellbutrin (bupropion).

I believe her dosages are:

- Effexor XR: 75 mg/day

- Wellbutrin SR: 150 mg/day

She seemed to have had a therapeutic "window" with Effexor. She began to feel better at 75 mg/day. When her doctor raised the dosage higher (150 mg ?), she felt worse. When the dosage was reduced to 75 mg/day, she felt better again. This combination has been working for her for over two years.

She described her response to Wellbutrin alone as giving her more energy, however it did little for her motivation (wanna do's). Effexor alone gave her more motivation, but no energy to do anything. I know it sounds silly, but 1+1=2.

Good luck.


- Scott


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