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Re: Celexa and side effects -- read this

Posted by Manny on January 25, 2000, at 8:02:15

In reply to Re: Celexa and side effects -- do they end?, posted by Bob on January 24, 2000, at 19:03:48

The product label for Celexa says the following under "carcinogenesis": Citalopram was administered in the diet to ....strain mice and ...strain rats for 18 and 24 months, respectively. There was no evidence of carcinogeneicity of citalopram in mice receiving up to 240 mg/kg/day ,which is 20 times the maximum recommended human daily dose of 60 mg ... THERE WAS AN INCREASED INCIDENCE OF SMALL INTESTINE CARCINOMA IN RATS RECEIVING 8 OR 24 MG/KG/DAY, DOSES WHICH ARE APPROXIMATELY 1.3 AND 4 TIMES MAXIMUM RECOMMENDED HUMAN DAILY DOSE ... A NO EFFECT DOSE FOR THIS FINDING WAS NOT ESTABLISHED. THE RELEVANCE OF THESE FINDINGS TO HUMANS IS UNKNOWN.
What do you people feel about this (the part in caps)? What do your Dr's say. I am on the drug but concerned. Please share your thoughts.


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