Posted by Elizabeth on March 6, 2000, at 21:53:45
In reply to Re: What do you know about...., posted by Noa on March 6, 2000, at 17:25:08
> Anyway, re: your question, the only TCA I ever tried was amytriptiline, which I can never spell correctly, and of course I could just say, Elavil, but there is something about that brand name I dislike.
It's kind of hokey, isn't it?
> It was the very first AD I ever tried, so I was not on anything else. Elizabeth, I "wigged out", meaning had a severe reaction, in which the following happened simultaneously: I was so hyped up and agitated, almost climbing the walls. The only thing keeping me from actually climbing the walls was the second thing, which was I was extremely sedated, to the point that my speech was slurred, my muscle coordination minimal, I could barely stand up and walk without holding on to the walls. I looked drunk as a skunk, only on the inside I was speeeeeeeeeeding. And this was from just one 25 mg. dose. I think all of this is the anticholinergic effects, because I used to get a very very mild form of the same reaction from benadryl and other antihistamines.
Have you thought about trying one of the other TCAs that have less anticholinergic and antihistaminic activity? Desipramine is the one I'm thinking of, specifically; it's very mild in that regard, and most people seem to tolerate it better than the other ones. Amitriptyline probably has the nastiest side effects of them all, overall.
poster:Elizabeth
thread:25503
URL: http://www.dr-bob.org/babble/20000302/msgs/26178.html