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Re: Question for AndrewB....

Posted by ash on March 28, 2000, at 10:56:55

In reply to Re: Question for AndrewB...., posted by AndrewB on March 28, 2000, at 9:43:57

Hello AndrewB:

My sleepdoc has prescribed Permax (pergolide) 0.4 mg for me for PLMD (Periodic Leg Movement Disorder) a cousin of RLS (Restless Leg Syndrome). Permax, as I am sure you are aware, is another Parkinson's medication like Mirapex but acts on the D1-D2 dopamine receptors. Permax has helped in reducing my PLMD but has had no beneficial effect on my long-time double depression .

Mirapex is another medication that is helpful in PLMD and your post makes me wonder if switching from Permax to Mirapex might have a dual benefit for my PLMD as well as depression. What dose of Mirapex are you on? Do you think the fact that I have PLMD makes it any more or less likely that my treatment-resistant depression would respond to a high dose of Mirapex as an augmentation agent to SSRI's? Any thoughts would be appreciated.

Thanks, Ash


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