Posted by JohnL on April 14, 2000, at 3:57:09
Hi all,
Why is it that France invents some of the world's best yet most unknown medications? I don't know what's in French drinking water, but whatever it is it sure seems to give them an edge when it comes to inventing fantastic medications.
Adrafinil and Amisulpride have nearly completely conquered my longstanding resistant depression. I've been amazed, yet have been reluctant to share the good news because I wanted to be sure it wasn't another short-lived tease. I think this time it's for real. Adrafinil and Amisulpride are wonderful medications.
I've taken Amisulpride before with Prozac, and it was helpful in social situations, but didn't address my anhedonia. So I'm pretty sure it's the Adrafinil that is doing the work. I could probably drop the Amisulpride to see, but my hunch is the Adrafinil is the wonderdrug in my small cocktail.
I'm actually showing interest in doing things, anticipating the 'fun' of planning different activities. For the last three years I've watched my yard go to weeds. The beach is just a 10 minute walk away, yet I have had no interest to go there--and haven't gone there--in three years. Now I'm eagerly planning on where to put fruit trees, cleaning up the weeds, planning all kinds of flower and vegie gardens. Walking down to the beach and laying in the sun sounds like fun. And I'm even pondering picking up my guitar again and blowing off the dust. Amazing! I think over the years of depression my subdued interests have changed, but it is sssooo good to actually have interest in something again.
Adrafinil comes on slowly, over about two weeks. After some very lousy sleep during the first week I now sleep very good and wake wanting to do things. I have NNOO side effects. Actually, the only side effect is if I stand up too quickly I get dizzy for a second. That's it.
Current cocktail is: Adrafinil 600mg, Amisulpride 100mg, Remeron 7.5mg, St Johnswort 900mg. But I truly think the powerhorse is the Adrafinil. The others provide benefits, but the Adrafinil is the star of the show. I was amazed at how well and how quickly Adrafinil and St Johnswort complimented each other. What a fantastic combination. Unbelievable. With such a simple and highly pleasing combination, I cringe in disgust at all the other drugs I've tried...every SSRI, several TCAs, one MAOI, every augmentation imaginable, mood stabilizers, Naltrexone, on and on.
What a long waste of time, and a long torturous nightmare it has been, to finally get where I am. And to think that of all the drugs our FDA approves, the best ones aren't even on their list. Thank God for French scientists and overseas mailorders. The best drugs the USA has to offer pale in comparison to other drugs around the world.
So I'm here to announce, finally, that Adrafinil is the first and only medication among dozens that has treated my longstanding stubborn anhedonia. I'm not 100%, but closer than I've ever been. And it's still early. So to Adrafinil I say....SALUTE!!! :) JohnL
poster:JohnL
thread:29956
URL: http://www.dr-bob.org/babble/20000411/msgs/29956.html