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Re: Cam - serotonin and dopamine opposition

Posted by Cam W. on April 17, 2000, at 21:49:55

In reply to Re: Cam - serotonin and dopamine opposition, posted by boB on April 17, 2000, at 20:48:41


boB - I am woefully deficient in my understanding of the mechanisms behind how working memory becomes long term memory. I think it has more to do with the NMDA (N-methyl-D-aspartate?) receptor complex. These receptor complexes have a near saturation of glycine attached to them (a basal glycine level) and are stimulated by the neurotransmitter glutamate. I am not sure whether norepinephrine triggers (or amplifies) the process in which the NMDA complex 'lays down' the neural circuitry for long term memory, but I'll bet it involves a number of neurotransmitters. (Actually I am not positive NMDA is involved, but I have a nagging feeling it is - I need my file cabinet at home rather than at work).

Like yourself, I am piecing together this information from a number of different articles and I am still missing several of the puzzle pieces. Sorry that I cannot help more than this. If I remember which file I put these articles (either in neuroanatomy or antipsychotics or schizophrenia or consciousness) and can find them, I will try to get back to you on this tomarrow. - Cam W.


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poster:Cam W. thread:29285
URL: http://www.dr-bob.org/babble/20000411/msgs/30405.html