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Re: Mirapex vs. amisulpride

Posted by AndrewB on April 21, 2000, at 15:04:26

In reply to Re: Mirapex vs. amisulpride, posted by Scott L. Schofield on April 21, 2000, at 13:20:36

Scott,

You would think that amisulpride at low doses might might decrease prolactin but I have double checked on this point and amisulpride raises prolactin levels, especially in women, at both lwer and higher doses. This can result in missed menses and breast swelling, even lactation. Sulpiride is very similar to amisulpride and it caused KarenB to miss her menses. The exact percentage of women who experience these endrocrinological effects when taking amisulpride in low doses is hard to say exactly. According to depression studies though, it seems around 5% of women stop amisulpride due to this effect, maybe as high as 10%. Since Mirapex raises prolactin levels it may indeed counter this effect. Good point Scott.

AndrewB


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