Posted by Andre Allard on May 10, 2000, at 3:37:22
In reply to EVERYONE! I need anew drug, posted by afatchic on May 8, 2000, at 20:01:11
> I've been so impressed with the intellect and knowledge displayed on this board. I need your recommendations. I've suffered from dysthimia all my life with lapses into major depression. I inherited the condition from my dad who self-medicated with alcohol until it killed him. I finally got up the courage and talked to a doctor I trusted. It really does help working in the medical field when you can get to know the doctors as people first. Here's my history: I started on trazadone in 1989, it took about 3 weeks but the results were wonderful. I felt "normal". I was able to experience happiness. After 4 years on trazadone, I had gained about 40 pounds even though I was a "health freak". I thought the weight gain was worth the emotional well-being but, being in the Air Force, the weight gain was ruining my career. I reluctantly switched to prozac, which worked just as well for me. I stopped having orgasms and stopped wanting to have sex but I didn't learn that it was caused by the Prozac until I'd taken it for 5 years (great for a marriage). That brings me up to the present. I've been on wellbutrin now for about a month and it doesn't seem to be working. I have noticed that I don't have much of desire to drink alcohol but that's the only positive change. Otherwise, I am so irritable! People in stores make me angry for petty things and I've been snapping at my husband and son. Does anyone have any advice for me? I'm looking for a drug that allows me to be happy, doesn't make me fat, doesn't make me frigid, and doesn't make me a witch. Anybody?
So you are looking for something that makes you happy, but doesn't make you fat, frigid or a witch. It seems you might have a bit of a problem. The thing is that AD's that do not cause weight gain tend to make you frigid and a witch (prozac, zoloft, effexor, wellbutrin). The AD's that do not make you frigid and a witch, at times, cause weight gain (serzone, remeron, paxil). This means you are looking for something in the middle. You might want to try a new class of meds called RIMA's (reversable inhibitor of manoamine oxidase). This class is similiar to the older MAOI's in its ability to alter the function of manoamine oxidase which in turn effects seritonin, norepinephrine and dopamine. The difference with the newer RIMA's is they do not interact with tyramine which means there is no restricted diet. The drug is called manerix. It is only available in Canada at this time (I do not know where you live). Something else you might want to try is Celexa, Luvox or even Zoloft. If one of these SSRI's makes you frigid, you can try adding trazadone at bedtime. I am on effexor which makes me frigid and a witch. When I take trazadone, as I have suggested, I am not frigid but am still a witch. Better than nothing I suppose. You can discuss these suggestions with the doc. Let us know how things turn out. Good luck!
poster:Andre Allard
thread:32819
URL: http://www.dr-bob.org/babble/20000508/msgs/33006.html