Posted by Jade on May 22, 2000, at 22:21:25
In reply to Re: Rather not die alone (Risperidone), posted by PeterJ on May 22, 2000, at 0:43:42
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> > Does Risperidone result in weight gain as a function of appetite? or does it cause some metabolic change?
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> Risperidone can cause weight gain by both mechanisms. Risperidone blocks histamine, serotonin and dopamine receptors. This results in an increase in appetite, which is difficult to control. There is also some metabolic effect due to the increase in the hormone prolactin which may occur. The metabolic effect is probably relatively small at the dose you are taking, but it can be a factor.
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> Many of the new antipsychotics such as olanzepine and clozapine cause more weight gain than risperidone does. There are older antipsychotics which don't cause weight gain. Molindone is one. But these drugs are more likely than Risperidone to cause movement disorders (tardive dyskinesia).
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> PeterI am a student who is curious about why some individuals do not experience weight gain on these medications.
Have animal studies been done re: weight gain and antipsychotics?
Do the percentages vary with each drug?
Can someone guide me to resources for the above questions?
Thank you
Jade
poster:Jade
thread:32301
URL: http://www.dr-bob.org/babble/20000517/msgs/34350.html