Posted by JohnL on May 25, 2000, at 2:47:14
In reply to Re: Provigil, posted by SLS on May 18, 2000, at 10:43:24
> John, where can I find some information comparing the efficacy of Provigil and adrafinil?
>
>
> - ScottScott,
I don't think there is any. These are not widely used or studied drugs. All the efficacy studies I've seen, which are hard to come by, had to do with narcolepsy or wakefullness only.In the Physician's Desk Reference Book, it's not uncommon for a drug to occupy 2 or 3 pages in small print. Modafinil wasn't even a whole page. And since Adrafinil is non-FDA, it isn't in there at all. And while the book cites clinical trials of whatever med, I don't recall seeing any listed for Modafinil, other than something about monkeys finding a moderate similarity to amphetamines. (I always wondered, how do they know that? Did they ask them? :-) )
As usual, I guess there's no substitute for personal trial. Even if we had tons of info on these drugs, you and I have both seen how strikingly different people respond from what literature would suggest.
JohnL
poster:JohnL
thread:33636
URL: http://www.dr-bob.org/babble/20000517/msgs/34564.html