Posted by Rick on June 12, 2000, at 0:25:59
In reply to Re-Andre #1:SOC PHOBIA COCKTAIL--WOW!!: Survey..., posted by Rick on June 12, 2000, at 0:06:48
(part 3 of ?? parts)
In a double-blind, placebo-controlled study by noted Social Phobia researcher J.R. Davidson at Duke University, eight weeks of daily Klonopin produced the highest response rate ever seen in a Social Phobia study. In fact, the response was much higher than in any placebo-controlled *antidepressant* study through today (although the response rate for the AD Nardil was nearly as high). Side effects were minimal, there was no manic behavior, and follow-up studies have demonstrated maintained efficacy without increased dosage, as well as a general lack of withdrawal problems.
As for developing tolerance, we can certainly dismiss that in my case. I started at 2.5 - 3.0 mg per day about a year ago, and even before adding any other meds, I had reduced that to 1.5. Indeed, 1.5-2.0 worked MUCH better for me than 2.5-3.0. At the higher dosages the Klonopin was substantially LESS effective, with the extra mg adding nothing but fatigue and fogginess. This is consistent with study after study that has debunked the ever-increasing-dose myth by showing that people who are taking benzos chronically for *anxiety disorders* tend to require less and less over time for efficacy, rather than more. Frankly, it pains me to repeatedly see or hear references to a widely-referenced Brazilian study on the web that suggests 3.0-6.0 mg/day for Social Phobia! While high doses are necessary in treating epilepsy, Social Phobia should rarely require more than 3.0 mg/day of clonazepam. So many people seem to have this terribly faulted notion that more is always better, especially for something that can offer fairly quick results. (Maybe that's what we're conditioned to expect, living in a Super-Sized, Over-Stuffed, Mega-Gulp society). I am continually dismayed to see that Dr. Bob continues to put a black eye on this other-wise wonderful site by continuing to feature this article as his ONLY article regarding treatment of Social Phobia.
BTW, How much WERE you taking during those prese
poster:Rick
thread:36883
URL: http://www.dr-bob.org/babble/20000610/msgs/36982.html