Posted by Cam W. on June 12, 2000, at 9:25:01
In reply to Cam - A question for a friend?, posted by Greg on June 12, 2000, at 8:59:22
Greg - A couple of questions about your friend. How long has she been taking the Zoloft this time? What dose is she taking? (ie could these be 'start-up' side effects?) How long did it take her to respond to Zoloft the 1st time?The tired feeling could also be an effect of the depression and the Zoloft hasn't kicked in, yet. Has it been the 8 weeks taking Zoloft this time?
Tell her not to give up too soon. The next step, if she needs to take it (if necessary) is to probably try another SSRI (since responded to one before). Maybe Paxil, especially if there is an anxiety component to this depression, due to it's reactive nature (ie a depression caused by an acute stressor).
As to differences antidepressant response between males and females, I kinda glanced at a recent article before I left on vacation about this. It would be available on-line from one of the nice Journals (eg Archives of General Psychiatry, other Archives, British Medical Journal, British Journal of Psychiatry, JAMA, American Family Physician, or perhaps a paper published on Medscape - I can't recall). This paper is at work and I won't be going in for a week or two, just yet. I think (but am not certain) that the conclusion of the study said that there are no "clinical" differences in response to antidepressants between the sexes, at least none we can utilize, yet.
Hope this helps - Cam W.
poster:Cam W.
thread:37011
URL: http://www.dr-bob.org/babble/20000610/msgs/37015.html