Posted by JohnL on June 28, 2000, at 5:18:02
In reply to provigil/adafinil, posted by shellie on June 27, 2000, at 18:47:53
Shellie,
Yes I've tried them both. Since we all respond so differently, I think it's difficult to tell which might work best with you. In my n=1 trial I found them to be dramatically different medications, with Adrafinil being the superior one. My preference for Adrafinil is based on its nearly nonexistent side effect profile and its smoothness. Provigil for me was rather harsh and rude. Since Adrafinil costs 1/10th of what Provigil costs, that's nice too. I will be interested to see which--if either--works best for you. I would be wonderful to see your suffering end with one of these.
It does seem like these two meds have stirred up a lot of interest at this board lately. That always seems to happen when someone finally finds the miraculous medication they've been searching for. The person with the miraculous response wants everyone else to experience the same joy. And everyone suffering wants to cling to a new source of hope. And there could be something inherently intriguing when the miraculous response is brought about by an unfamiliar med, a foreign med, or off-label use of some med.
I remember about a year or so ago WayneR found his cure with Naltrexone. For a while Naltrexone took the spotlight at this board. And Adam was in a clinical trial involving a patch version of Deprenyl. His good response stirred up a lot of enthusiasm in Deprenyl for a while. I think we see these cycles come and go periodically. Adrafinil/Provigil are a continuation of that pattern I think, primarily sparked by yet another miraculous therapeutic response with one of the board participants. If this is anything like previous patterns, the enthusiasm will fade as a few other people try these meds and discover they aren't as miraculous with them. You know how it goes...your mileage may vary. I would like to think these two meds could provide miracles for everyone. That's probably not realistic though. Regardless, they are good alternatives for those who have had disappointing results with more straight forward medication choices.
I'm in your corner cheering for you!
JohnL
poster:JohnL
thread:38485
URL: http://www.dr-bob.org/babble/20000619/msgs/38531.html