Posted by AndrewB on July 21, 2000, at 16:14:15
In reply to Amisulpride Question?, posted by michael on July 21, 2000, at 13:31:36
Good questions Micheal.
It seemed like the target presynaptic D2/D3 receptor wasn't getting stimulated by the amisulpride in your case. I wonder why. Maybe it has something to do with individual differences in receptor binding affinities.
I also wonder if someone who doesn't respond to amisulpride may respond to Pramipexole (Mirapex). Both amisulpride's and pramipexole's ultimate action is to correct D2/D3 hypofunction. But, while I respond robustly to amisulpride, I didn't respond to a fairly good trial with pramipexole. So I'm just wondering if the reverse can be true; someone who doesn't respond to amisulprride may respond to pramipexole.
AndrewB
poster:AndrewB
thread:40578
URL: http://www.dr-bob.org/babble/20000717/msgs/41138.html