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Re: Effexor XR and Pregnancy

Posted by tenuous on October 3, 2000, at 16:19:03

In reply to Re: Effexor XR and Pregnancy, posted by Ang on October 3, 2000, at 10:49:54

Here is a summary of the study of the effects on rats of
venlafaxine (Effexor) during pregnancy:

http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10347775&dopt=Abstract

I also found a summary of a study of venlafaxine (Effexor) in
human breast milk, but I can't find the website address right now.

Basically, during pregnancy the rats had reduced food intake
and this resulted in lower birth weights. However, at the time of
weaning the weight of the pups was comparable to the control
group. There was no difference in the number of live pups at
birth, stillbirths, mortality during lactation (breast-feeding),
or the manifestation of serotonergic syndrome in adult rats
(whatever serotonergic syndrome is ?!?!).

As for lactation, the drug DOES get secreted in the milk and
showed up in the blood of the infants. However, the infants were
healthy and showed NO ADVERSE EFFECTS.



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