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Re: Selegeline/Rebox. AndrewB/leonardo » JahL

Posted by Leonardo on November 1, 2000, at 11:05:04

In reply to Re: Selegeline/Rebox. AndrewB/leonardo, posted by JahL on October 28, 2000, at 12:11:26

FYI I happen to have just started a low dose trial of selegiline. I recently dropped the rebox/paxil and tried wellbutrin 300mg for 3 weeks, with no improvement. I am now trying selegeline 2.5mg per day, and noticed a big boost in energy on the first day. I also took 2mg rebox later that day, which seemed to make things worse, so I've dropped that now. Its early days of course, but I am getting much better mental clarity and help with motivation than with any of the other ADs I've tried so far. If this works, it could be the dopamaine effect, the others I've tried don't have a strong dopamine effect (paxil, rebox, wellbutrin, remeron).

Leonardo

> Thanks for your responses everyone. Think I've got what I was after (tho' I'd still like to hear from you, Leonardo)
>
> Just to clarify. I know low & slow's the preferred method but I am doing this on the direction of my pdoc. He knows I'd rather put up with the side effects and find out as quickly as possible if the drug's gonna work. I've got dozens more meds to get through....!
>
> Andrew, thanx 4 the detailed reply. I am intrigued by the low dose selegeline (like the sound of 'dramatic results') However I could not commit to a 45+ days trial w/o some guarantee of success.
>
> How compatible would such a low dose be with other agents? I am thinking of course of running concurrent trials (with the requisite caution) Bear in mind I am only talking about 1 other agent at a time (not my previous 5!) I know polypharmacy can cloud results but with just 2 agents a simple process of elimination should separate things (?)
>
> Thanx for any thoughts,
>
> Jah.


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