Posted by JohnL on January 24, 2001, at 2:47:37
In reply to Adrafinal and Amisulpride---John and Andrew, posted by Dwight on January 24, 2001, at 0:02:47
> It's obvious that both you guys really like these meds. But you also talk about them as if you have some proof that they work for everybody else with low motivation, social anxiety symptoms. Who else besides you guys? I have the drugs in my cabinet, and I tried them. I didn't notice much. Maybe I'll try them again. You guys are so damn inspiring about it. But how do you know it works for other people?
You make a good point. I must apologize, I don't mean to sound like a salesman for these drugs, though I probably do at times. :-)
Based on clinical trials, the odds for success are about 70%. Personally I get the impression the odds for success are probably closer to 80% or higher. That's because unlike reuptake inhibitors, Adraf or Amis can provide benefits even to normal people. That is based on literature from non-peer-reviewed literature and comments from others. Nothing scientific, just a general impression.
I usually think these drugs have the highest potential for success in certain situations. That is, when several reuptake inhibitors have already been tried, maybe mood stabilizers, and this or that.
I am disappointed these drugs didn't help you. Obviously when one of us finds a drug that really works, we want it to work for everyone. I remember WayneR who used to be a regular here found miraculous cure with Naltrexone. Some of us jumped on the bandwagon and tried it, but most of us found little benefit. I'm sure that must have been distressing to Wayne. I experience the same feelings when my favorite drugs are not useful to someone else. If you wanted to take a second look, I would say that if you are experiencing absolutely no benefit within two weeks to three weeks, then they probably aren't right for you. That would likely mean that your dopamine function and your NE function is just fine, and that whatever chemistry is causing your symptoms lies elsewhere. Due to the low incidence of side effects, the low cost, and ease of purchasing, I would say they are worth a second look-see.
John
poster:JohnL
thread:52374
URL: http://www.dr-bob.org/babble/20010122/msgs/52376.html