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Re: Depression--Help

Posted by Lee on January 27, 2001, at 9:34:22

In reply to Depression--Help, posted by Kiris on January 26, 2001, at 13:02:13

> I am currently taking 5 75 mg pills of Effexor XR each morning for depression and it has stopped working. I now feel very hopeless and tearful at inappropriate things. I also notice that I am a bit sleepy but I am not sure what to add. Any thoughts? I ahve taken Prozac by itself, Zoloft by itself, remeron by itself and Paxil by itself with no relief. Effexor XR was the first thing that made a difference but then each time I got my period I would get depressed again and would add another pill and it would help a bit. Then I'd get my period again and the depression would get worse and I'd add another pill. I was wondering if anyone has run into this and if you found the addition of anything else to be helpful for depression/hopelessness but soemthign that will not zonc me out anymore. Thanks so much.


I, also, am on Effexor and have experienced a worsening/return of depression due to hormonal changes.

Also, like you, I have trialed Prozac, Paxil, Zoloft, Remeron with little or no response. No response from SSRIs and some relief from Effexor could mean that you respond well to meds that target the neurotransmitter norepinephrone or dopamine. (MANY people who contribute to this forum can speak more intelligently about possible links between symptomology and neurotransmitters.)

I have experienced moderate to great improvement in mood, energy, motivation and sleep by augmenting Effexor with Amisulpride and Provigil.

I hope this information is helpful. Hang in there - there are many safe drug combinations and recent drugs that could help.


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poster:Lee thread:52621
URL: http://www.dr-bob.org/babble/20010122/msgs/52681.html