Posted by SLS on January 30, 2001, at 16:46:42
In reply to Re: Celebrex aggravating depression! WHY? » nhgrandma, posted by Sunnely on January 25, 2001, at 20:05:28
Dear Sunnely,
Your post was wonderfully executed, and I profitted from it greatly. I will need to reread it a few times yet. I interpret your wording that the various cytokines can either enhance or suppress the immune system. Is this true?
Would low dosages of Elavil h.s. be a reasonable remedy for both the neck pain and the Celebrex-induced exacerbation of depression?
I work real hard not to ask you what background or profession you are involved with to be so knowledgeable and objective. I won't ask that question now. Make believe I never brought it up.
I would like to extend to you a sincere "thank you" for your contributions. I am appreciative of the time it must take to compose such wonderful posts.
Again, make believe I never asked.
- Scott> > Why do anti-inflamatory medications (the latest being Celebrex) aggravate depression? I am currently on 20 mg Celexa and .50 mg Clonazepam for sleep. The combo has been working great until I added Celebrex for neck pain. I have experimented over the last 3 months and have found a definite correlation between Celebrex and increased depression. But the pain diminishes. Bummer. I do not understand. Is there any reason or answer for this problem? Thanks
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> To conlude, the main issue is not whether patients with psychiatric disorders should avoid using NSAIDs; instead, given the available evidence, anti-inflammatory drugs warrant heightened scrutiny for their potential effects on the way they affect mood, cognition, and behavior. Indeed, NSAIDs do in fact appear to be "emotion-modulating drugs." In this regard, they may have effects similar to corticosteroids. Therefore, clinicians and patients alike must be aware of potential adverse psychiatric events with the use of these drugs.
poster:SLS
thread:51763
URL: http://www.dr-bob.org/babble/20010122/msgs/52981.html